Thrombin inhibitor 5

Cat. No.: HY-148037 Purity: 99.82%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Thrombin inhibitor 5 (compound 385) is a thrombin inhibitor, with IC₅₀s ranging from 0.1 μM to 1 μM. Thrombin inhibitor 5 can be used for research of venous thromboembolism.

For research use only. We do not sell to patients.

Thrombin inhibitor 5 Chemical Structure

CAS No. : 328108-09-4

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 176	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 176	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 160	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 550	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Thrombin inhibitor 5 (compound 385) is a thrombin inhibitor, with IC₅₀s ranging from 0.1 μM to 1 μM. Thrombin inhibitor 5 can be used for research of venous thromboembolism^[1].

IC₅₀ & Target

thrombin^[1]

Molecular Weight

264.21

Formula

C₁₁H₉FN₄O₃

CAS No.

328108-09-4

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=NNC(NC(C2=CC=C(F)C=C2)=O)=N1)OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 31.25 mg/mL (118.28 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7849 mL	18.9243 mL	37.8487 mL
5 mM	0.7570 mL	3.7849 mL	7.5697 mL
10 mM	0.3785 mL	1.8924 mL	3.7849 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.82%

Select Batch:

Data Sheet (269 KB) SDS (251 KB)

COA (247 KB) HNMR (261 KB) LCMS (271 KB)

Handling Instructions (2659 KB)

References

[1]. Short K M, et al. Multisubstituted aromatic compounds as inhibitors of thrombin and their preparation: US, US20170326125[p]. 2017-11-16.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7849 mL	18.9243 mL	37.8487 mL	94.6217 mL
	5 mM	0.7570 mL	3.7849 mL	7.5697 mL	18.9243 mL
	10 mM	0.3785 mL	1.8924 mL	3.7849 mL	9.4622 mL
	15 mM	0.2523 mL	1.2616 mL	2.5232 mL	6.3081 mL
	20 mM	0.1892 mL	0.9462 mL	1.8924 mL	4.7311 mL
	25 mM	0.1514 mL	0.7570 mL	1.5139 mL	3.7849 mL
	30 mM	0.1262 mL	0.6308 mL	1.2616 mL	3.1541 mL
	40 mM	0.0946 mL	0.4731 mL	0.9462 mL	2.3655 mL
	50 mM	0.0757 mL	0.3785 mL	0.7570 mL	1.8924 mL
	60 mM	0.0631 mL	0.3154 mL	0.6308 mL	1.5770 mL
	80 mM	0.0473 mL	0.2366 mL	0.4731 mL	1.1828 mL
	100 mM	0.0378 mL	0.1892 mL	0.3785 mL	0.9462 mL