2. Metabolic Enzyme/Protease
  3. Proteasome
  4. Thrombin inhibitor 5

Thrombin inhibitor 5 (compound 385) is a thrombin inhibitor, with IC50s ranging from 0.1 μM to 1 μM. Thrombin inhibitor 5 can be used for research of venous thromboembolism.

For research use only. We do not sell to patients.

Thrombin inhibitor 5 Chemical Structure

Thrombin inhibitor 5 Chemical Structure

CAS No. : 328108-09-4

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 176 In-stock
Solution
10 mM * 1 mL in DMSO USD 176 In-stock
Solid
5 mg USD 160 In-stock
10 mg USD 250 In-stock
25 mg USD 550 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Thrombin inhibitor 5 Related Antibodies

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Description

Thrombin inhibitor 5 (compound 385) is a thrombin inhibitor, with IC50s ranging from 0.1 μM to 1 μM. Thrombin inhibitor 5 can be used for research of venous thromboembolism[1].

IC50 & Target

thrombin[1]
Molecular Weight

264.21

Formula

C11H9FN4O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=NNC(NC(C2=CC=C(F)C=C2)=O)=N1)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 31.25 mg/mL (118.28 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7849 mL 18.9243 mL 37.8487 mL
5 mM 0.7570 mL 3.7849 mL 7.5697 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7849 mL 18.9243 mL 37.8487 mL 94.6217 mL
5 mM 0.7570 mL 3.7849 mL 7.5697 mL 18.9243 mL
10 mM 0.3785 mL 1.8924 mL 3.7849 mL 9.4622 mL
15 mM 0.2523 mL 1.2616 mL 2.5232 mL 6.3081 mL
20 mM 0.1892 mL 0.9462 mL 1.8924 mL 4.7311 mL
25 mM 0.1514 mL 0.7570 mL 1.5139 mL 3.7849 mL
30 mM 0.1262 mL 0.6308 mL 1.2616 mL 3.1541 mL
40 mM 0.0946 mL 0.4731 mL 0.9462 mL 2.3655 mL
50 mM 0.0757 mL 0.3785 mL 0.7570 mL 1.8924 mL
60 mM 0.0631 mL 0.3154 mL 0.6308 mL 1.5770 mL
80 mM 0.0473 mL 0.2366 mL 0.4731 mL 1.1828 mL
100 mM 0.0378 mL 0.1892 mL 0.3785 mL 0.9462 mL
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Thrombin inhibitor 5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thrombin inhibitor 5328108-09-4Thrombin inhibitor5Thrombin inhibitor-5Proteasomemultisubstituted pyrazole triazolevenous thromboembolismInhibitorinhibitorinhibit

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