Tiamenidine hydrochloride (Synonyms: HOE 440 hydrochloride)

Cat. No.: HY-112074A: FAQs
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Tiamenidine hydrochloride (HOE 440 hydrochloride) is a centrally acting α1-adrenergic receptor antagonist with hypotensive activity. Tiamenidine hydrochloride regulates blood pressure levels by binding to α1 receptors. Tiamenidine hydrochloride can be used in the study of hypertension.

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Tiamenidine hydrochloride Chemical Structure

CAS No. : 51274-83-0

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Other Forms of Tiamenidine hydrochloride:

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α adrenergic receptor β adrenergic receptor

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Description	Tiamenidine hydrochloride (HOE 440 hydrochloride) is a centrally acting α1-adrenergic receptor antagonist with hypotensive activity. Tiamenidine hydrochloride regulates blood pressure levels by binding to α1 receptors. Tiamenidine hydrochloride can be used in the study of hypertension^[1].
Molecular Weight	252.16
Formula	C₈H₁₁Cl₂N₃S
CAS No.	51274-83-0
SMILES	ClC1=C(NC2=NCCN2)C(C)=CS1.Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. D M Roden, et al. Electrophysiologic and hemodynamic effects of chronic oral therapy with the alpha 2-agonists clonidine and tiamenidine in hypertensive volunteers. Clin Pharmacol Ther. 1988 Jun;43(6):648-54. [Content Brief] [2]. Quantitative determination of tiamenidine hydrochloride in human serum using gas chromatography mass spectrometry

Tiamenidine hydrochloride Related Classifications

Cardiovascular Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Tiamenidine51274-83-0HOE 440HOE440HOE-440Adrenergic ReceptorBeta Receptorα2-Adrenergic Receptor AgonistInhibitorinhibitorinhibit

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Tiamenidine hydrochloride (Synonyms: HOE 440 hydrochloride)

Other Forms of Tiamenidine hydrochloride:

Tiamenidine hydrochloride Related Antibodies

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Biological Activity

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