2. Anti-infection
  3. HIV
  4. Tigloylgomisin P

Tigloylgomisin P, a lignin, has anti-HIV activity with an EC50 of 37 μM. Tigloylgomisin P has anticancer effect.

For research use only. We do not sell to patients.

Tigloylgomisin P Chemical Structure

Tigloylgomisin P Chemical Structure

CAS No. : 69176-51-8

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Based on 1 publication(s) in Google Scholar

Tigloylgomisin P Related Antibodies

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  • Biological Activity

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Description

Tigloylgomisin P, a lignin, has anti-HIV activity with an EC50 of 37 μM. Tigloylgomisin P has anticancer effect[1][2].

Cellular Effect
Cell Line Type Value Description References
H9 IC50
> 49 μM
Compound: tigloylgomisin P
Cytotoxicity against human H9 cells after 4 days
Cytotoxicity against human H9 cells after 4 days
[PMID: 17190445]
H9 EC50
37 μM
Compound: tigloylgomisin P
Antiviral activity against HIV1 3B in H9 cells after 4 days by p24-antigen ELISA
Antiviral activity against HIV1 3B in H9 cells after 4 days by p24-antigen ELISA
[PMID: 17190445]
In Vitro

Tigloylgomisin P displays weak cytotoxicity against A549 cells (GI50=18.77 μM), epidermoid carcinoma of the nasopharynx (KB; GI50=13.91 μM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tigloylgomisin P Related Antibodies
Molecular Weight

514.56

Formula

C28H34O9
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C/C=C(C)/C(O[C@@H]([C@](C)(O)[C@@H](C)C1)C2=CC(OC)=C(OC)C(OC)=C2C3=C1C=C4OCOC4=C3OC)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (97.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9434 mL 9.7170 mL 19.4341 mL
5 mM 0.3887 mL 1.9434 mL 3.8868 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9434 mL 9.7170 mL 19.4341 mL 48.5852 mL
5 mM 0.3887 mL 1.9434 mL 3.8868 mL 9.7170 mL
10 mM 0.1943 mL 0.9717 mL 1.9434 mL 4.8585 mL
15 mM 0.1296 mL 0.6478 mL 1.2956 mL 3.2390 mL
20 mM 0.0972 mL 0.4859 mL 0.9717 mL 2.4293 mL
25 mM 0.0777 mL 0.3887 mL 0.7774 mL 1.9434 mL
30 mM 0.0648 mL 0.3239 mL 0.6478 mL 1.6195 mL
40 mM 0.0486 mL 0.2429 mL 0.4859 mL 1.2146 mL
50 mM 0.0389 mL 0.1943 mL 0.3887 mL 0.9717 mL
60 mM 0.0324 mL 0.1620 mL 0.3239 mL 0.8098 mL
80 mM 0.0243 mL 0.1215 mL 0.2429 mL 0.6073 mL
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Tigloylgomisin P Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tigloylgomisin P69176-51-8HIVHuman immunodeficiency virusInhibitorinhibitorinhibit

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