2. Cell Cycle/DNA Damage Apoptosis
  3. Topoisomerase Apoptosis
  4. Topoisomerase II inhibitor 10

Topoisomerase II inhibitor 10 (compound 32a) is a potent topoisomerase II inhibitor with an IC50 value of 7.45 μM. Topoisomerase II inhibitor 10 causes cell cycle arrest at G2-M phase and induces apoptosis of HepG-2 cells. Topoisomerase II inhibitor 10 has excellent anti-proliferative activities against HepG-2, MCF-7, and HCT-116 cells.

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Topoisomerase II inhibitor 10 Chemical Structure

Topoisomerase II inhibitor 10 Chemical Structure

CAS No. : 2488208-96-2

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Topoisomerase II inhibitor 10 Related Antibodies

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Description

Topoisomerase II inhibitor 10 (compound 32a) is a potent topoisomerase II inhibitor with an IC50 value of 7.45 μM. Topoisomerase II inhibitor 10 causes cell cycle arrest at G2-M phase and induces apoptosis of HepG-2 cells. Topoisomerase II inhibitor 10 has excellent anti-proliferative activities against HepG-2, MCF-7, and HCT-116 cells[1].

IC50 & Target[1]

Topoisomerase II

7.45 μM (IC50)

Molecular Weight

572.55

Formula

C27H20N6O7S
CAS No.
SMILES

O=C(O)C1=CC=C(NC(CSC2=NN=C3N2N(CC(NC4=CC=C(C(O)=O)C=C4)=O)C(C5=C3C=CC=C5)=O)=O)C=C1
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Purity & Documentation
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Topoisomerase II inhibitor 10 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Topoisomerase II inhibitor 102488208-96-2Topoisomerase II inhibitor10Topoisomerase II inhibitor-10TopoisomeraseApoptosisanticancerantiproliferativeHepG-2MCF-7HCT-116Inhibitorinhibitorinhibit

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