2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Topoisomerase II inhibitor 19

Topoisomerase II inhibitor 19 (compound 5h) is a DNA intercalator and topoisomerase II inhibitor (IC50 value of 0.34 μM). Topoisomerase II inhibitor 19 would induce detectable potent damage in ctDNA.

For research use only. We do not sell to patients.

Topoisomerase II inhibitor 19 Chemical Structure

Topoisomerase II inhibitor 19 Chemical Structure

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Topoisomerase II inhibitor 19 Related Antibodies

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Description

Topoisomerase II inhibitor 19 (compound 5h) is a DNA intercalator and topoisomerase II inhibitor (IC50 value of 0.34 μM). Topoisomerase II inhibitor 19 would induce detectable potent damage in ctDNA[1].

IC50 & Target[1]

Topoisomerase II

0.34 μM (IC50)

In Vitro

Topoisomerase II inhibitor 19 (compound 5h; 24 h) inhibits the cell proliferation of MCF-7 cells via cell cycle arrest at the S phase[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Topoisomerase II inhibitor 19 Related Antibodies
Molecular Weight

465.95

Formula

C27H16ClN3OS
SMILES

O=C1/C(C2=C3C1=CC=CC3=CC=C2)=N/N4C=C(C5=CC=C(Cl)C=C5)N(C6=CC=CC=C6)C4=S
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Topoisomerase II inhibitor 19 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Topoisomerase II inhibitor 19Topoisomerase II inhibitor19Topoisomerase II inhibitor-19TopoisomeraseDNA intercalatortopoisomerase IIcell cycle arrestInhibitorinhibitorinhibit

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Topoisomerase II inhibitor 19
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HY-162381
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