2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Topoisomerases/ribosomes-IN-1

Topoisomerases/ribosomes-IN-1 (compound 30f) is an inhibitor of ribosomes and topoisomerases, and has inhibitory effects on constitutively macrolide-resistant bacteria. Topoisomerases/ribosomes-IN-1 can inhibit bacterial protein synthesis (IC50: 0.647 μM) and DNA replication (IC50: 0.218 μM).

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Topoisomerases/ribosomes-IN-1 Chemical Structure

Topoisomerases/ribosomes-IN-1 Chemical Structure

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Topoisomerases/ribosomes-IN-1 Related Antibodies

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Description

Topoisomerases/ribosomes-IN-1 (compound 30f) is an inhibitor of ribosomes and topoisomerases, and has inhibitory effects on constitutively macrolide-resistant bacteria. Topoisomerases/ribosomes-IN-1 can inhibit bacterial protein synthesis (IC50: 0.647 μM) and DNA replication (IC50: 0.218 μM)[1].

Molecular Weight

1063.26

Formula

C53H83FN6O15
SMILES

CO/N=C1[C@H](C)[C@H](O2)[C@@](OC2=O)(C)[C@@H](CC)OC([C@H](C)[C@@H](OCCCOCCCN3CCN(C4=NC5=C(C(C(C(O)=O)=CN5CC)=O)C=C4F)CC3)[C@H](C)[C@@H](O[C@@H]6O[C@H](C)C[C@H](N(C)C)[C@H]6O)[C@@](OC)(C)C[C@H]/1C)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Topoisomerases/ribosomes-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Topoisomerases/ribosomes-IN-1TopoisomeraseInhibitorinhibitorinhibit

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