Topotecan acetate (Synonyms: SKF 104864A acetate; NSC 609669 acetate)

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Topotecan acetate is a topoisomerase inhibitor.

For research use only. We do not sell to patients.

Topotecan acetate Chemical Structure

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Other Forms of Topotecan acetate:

Topotecan Get quote

13 Publications Citing Use of MCE Topotecan acetate

: Topotecan acetate purchased from MedChemExpress. Usage Cited in: Nat Commun. 2019 Aug 21;10(1):3761. [Abstract]; WDR5 inhibitor OICR-9429 enhances the sensitivity of ovarian cancer to genotoxic chemotherapeutics in vivo. Representative images and the apoptotic rate the indicated chemotherapy-treated xenograft tumors.

: Topotecan acetate purchased from MedChemExpress. Usage Cited in: Nat Commun. 2019 Aug 21;10(1):3761. [Abstract]; IB analysis of the level of cleaved-caspase 3 and cleaved-PARP1 in the indicated chemotherapy-treated xenograft tumors. GAPDH served as the loading control.

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Description	Topotecan acetate is a topoisomerase inhibitor.
Molecular Weight	481.50
Formula	C₂₅H₂₇N₃O₇
CAS No.	123948-88-9
SMILES	O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O.CC(O)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (272 KB) Handling Instructions (2659 KB)
References	[1]. Kollmannsberger C, et al. Topotecan - A novel topoisomerase I inhibitor: pharmacology and clinical experience. Oncology. 1999;56(1):1-12. [Content Brief]

Topotecan acetate Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Topotecan123948-88-9SKF 104864ANSC 609669NSC609669NSC-609669TopoisomeraseInhibitorinhibitorinhibit

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Topotecan acetate (Synonyms: SKF 104864A acetate; NSC 609669 acetate)

Other Forms of Topotecan acetate:

Topotecan acetate Related Antibodies

13 Publications Citing Use of MCE Topotecan acetate

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All Topoisomerase Isoform Specific Products:

Biological Activity

Purity & Documentation

References

Customer Review

Topotecan acetate Related Classifications

Molarity Calculator

Dilution Calculator