Trametinib (Standard)

Cat. No.: HY-10999R Purity: ≥98%: FAQs
Handling Instructions

Molarity Calculator

Trametinib (Standard) is the analytical standard of Trametinib. This product is intended for research and analytical applications. Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC₅₀s of about 2 nM. Trametinib activates autophagy and induces apoptosis.

For research use only. We do not sell to patients.

Trametinib (Standard) Chemical Structure

CAS No. : 871700-17-3

Size	Price	Stock
5 mg	USD 95	Ask For Quote & Lead Time
10 mg	USD 145	Ask For Quote & Lead Time
25 mg	USD 260	Ask For Quote & Lead Time
50 mg	USD 360	Ask For Quote & Lead Time
100 mg	USD 500	Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

Product Information
Purity & Documentation
Customer Review

Description	Trametinib (Standard) is the analytical standard of Trametinib . This product is intended for research and analytical applications. Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC₅₀s of about 2 nM. Trametinib activates autophagy and induces apoptosis.
Molecular Weight	615.39
Formula	C₂₆H₂₃FIN₅O₄
CAS No.	871700-17-3
SMILES	CC(NC1=CC=CC(N(C2=O)C(C(C(N2C3CC3)=O)=C(N4C)NC5=CC=C(C=C5F)I)=C(C4=O)C)=C1)=O
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Trametinib (Standard) Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trametinib (Standard)871700-17-3MEKAutophagyApoptosisMitogen-activated protein kinase kinaseMAPKKMAP2KAdjuvant-inducedarthritisAIAtypeIIcollageninducedCIAorallyInhibitorinhibitorinhibit

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