2. Anti-infection Autophagy
  3. Bacterial Fungal Autophagy Antibiotic
  4. Triclosan-d3

Triclosan-d3 is the deuterium labeled Triclosan. Triclosan is an antibacterial and antifungal agent found in consumer products, including soaps, detergents, toys, and surgical cleaning treatments[1][2].

For research use only. We do not sell to patients.

Triclosan-d<sub>3</sub> Chemical Structure

Triclosan-d3 Chemical Structure

CAS No. : 1020719-98-5

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Based on 1 publication(s) in Google Scholar

Other Forms of Triclosan-d3:

Triclosan-d3 Related Antibodies

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Triclosan-d3 is the deuterium labeled Triclosan. Triclosan is an antibacterial and antifungal agent found in consumer products, including soaps, detergents, toys, and surgical cleaning treatments[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Triclosan-d3 Related Antibodies
Molecular Weight

292.56

Formula

C12H4D3Cl3O2
CAS No.
Unlabeled CAS

3380-34-5
Appearance

Solid

Color

White to off-white

SMILES

OC1=CC(Cl)=CC=C1OC2=C(Cl)C([2H])=C(Cl)C([2H])=C2[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (341.81 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 100 mg/mL (341.81 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 1 mg/mL (3.42 mM; ultrasonic and warming and heat to 80°C)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4181 mL 17.0905 mL 34.1810 mL
5 mM 0.6836 mL 3.4181 mL 6.8362 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.22%

COA (250 KB) HNMR (777 KB) RP-HPLC (559 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO / DMSO 1 mM 3.4181 mL 17.0905 mL 34.1810 mL 85.4526 mL
DMSO / DMSO 5 mM 0.6836 mL 3.4181 mL 6.8362 mL 17.0905 mL
10 mM 0.3418 mL 1.7091 mL 3.4181 mL 8.5453 mL
15 mM 0.2279 mL 1.1394 mL 2.2787 mL 5.6968 mL
20 mM 0.1709 mL 0.8545 mL 1.7091 mL 4.2726 mL
25 mM 0.1367 mL 0.6836 mL 1.3672 mL 3.4181 mL
30 mM 0.1139 mL 0.5697 mL 1.1394 mL 2.8484 mL
40 mM 0.0855 mL 0.4273 mL 0.8545 mL 2.1363 mL
50 mM 0.0684 mL 0.3418 mL 0.6836 mL 1.7091 mL
60 mM 0.0570 mL 0.2848 mL 0.5697 mL 1.4242 mL
80 mM 0.0427 mL 0.2136 mL 0.4273 mL 1.0682 mL
100 mM 0.0342 mL 0.1709 mL 0.3418 mL 0.8545 mL
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Triclosan-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Triclosan-d31020719-98-5BacterialFungalAutophagyAntibioticInhibitorinhibitorinhibit

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