2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Tulobuterol-d9 hydrochloride

Tulobuterol-d9 hydrochloride  (Synonyms: C-78-d9)

Cat. No.: HY-B1810S Purity: ≥99.0%
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Tulobuterol-d9 (hydrochloride) is the deuterium labeled Tulobuterol. Tulobuterol (C-78 free base) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength[1].

For research use only. We do not sell to patients.

Tulobuterol-d<sub>9</sub> hydrochloride Chemical Structure

Tulobuterol-d9 hydrochloride Chemical Structure

CAS No. : 1325559-14-5

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Based on 1 publication(s) in Google Scholar

Other Forms of Tulobuterol-d9 hydrochloride:

Tulobuterol-d9 hydrochloride Related Antibodies

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Description

Tulobuterol-d9 (hydrochloride) is the deuterium labeled Tulobuterol. Tulobuterol (C-78 free base) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tulobuterol-d9 hydrochloride Related Antibodies
Molecular Weight

273.25

Formula

C12H10D9Cl2NO
CAS No.
Unlabeled CAS

41570-61-0
Appearance

Solid

Color

White to off-white

SMILES

[2H]C(C(NCC(O)C1=CC=CC=C1Cl)(C([2H])([2H])[2H])C([2H])([2H])[2H])([2H])[2H].[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (365.97 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6597 mL 18.2983 mL 36.5965 mL
5 mM 0.7319 mL 3.6597 mL 7.3193 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.6597 mL 18.2983 mL 36.5965 mL 91.4913 mL
5 mM 0.7319 mL 3.6597 mL 7.3193 mL 18.2983 mL
10 mM 0.3660 mL 1.8298 mL 3.6597 mL 9.1491 mL
15 mM 0.2440 mL 1.2199 mL 2.4398 mL 6.0994 mL
20 mM 0.1830 mL 0.9149 mL 1.8298 mL 4.5746 mL
25 mM 0.1464 mL 0.7319 mL 1.4639 mL 3.6597 mL
30 mM 0.1220 mL 0.6099 mL 1.2199 mL 3.0497 mL
40 mM 0.0915 mL 0.4575 mL 0.9149 mL 2.2873 mL
50 mM 0.0732 mL 0.3660 mL 0.7319 mL 1.8298 mL
60 mM 0.0610 mL 0.3050 mL 0.6099 mL 1.5249 mL
80 mM 0.0457 mL 0.2287 mL 0.4575 mL 1.1436 mL
100 mM 0.0366 mL 0.1830 mL 0.3660 mL 0.9149 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Tulobuterol-d9 hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tulobuterol-d91325559-14-5C-78-d9Adrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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