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  4. UNC-CA2-103

UNC-CA2-103 (compound 128) is a potent inhibitor of Tousled like kinase 2 (TLK2), with the IC50 of 18 nM.

For research use only. We do not sell to patients.

UNC-CA2-103 Chemical Structure

UNC-CA2-103 Chemical Structure

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5 mg USD 150 In-stock
10 mg USD 240 In-stock
25 mg USD 480 In-stock
50 mg USD 730 In-stock
100 mg USD 1100 In-stock
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Based on 1 publication(s) in Google Scholar

UNC-CA2-103 Related Antibodies

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Description

UNC-CA2-103 (compound 128) is a potent inhibitor of Tousled like kinase 2 (TLK2), with the IC50 of 18 nM[1].

Molecular Weight

344.37

Formula

C20H16N4O2
Appearance

Solid

Color

Yellow to orange

SMILES

O=C(NC1=CC2=C(NC(/C2=C\C3=C(C)N=CN3)=O)C=C1)C4=CC=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (362.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9039 mL 14.5193 mL 29.0385 mL
5 mM 0.5808 mL 2.9039 mL 5.8077 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9039 mL 14.5193 mL 29.0385 mL 72.5963 mL
5 mM 0.5808 mL 2.9039 mL 5.8077 mL 14.5193 mL
10 mM 0.2904 mL 1.4519 mL 2.9039 mL 7.2596 mL
15 mM 0.1936 mL 0.9680 mL 1.9359 mL 4.8398 mL
20 mM 0.1452 mL 0.7260 mL 1.4519 mL 3.6298 mL
25 mM 0.1162 mL 0.5808 mL 1.1615 mL 2.9039 mL
30 mM 0.0968 mL 0.4840 mL 0.9680 mL 2.4199 mL
40 mM 0.0726 mL 0.3630 mL 0.7260 mL 1.8149 mL
50 mM 0.0581 mL 0.2904 mL 0.5808 mL 1.4519 mL
60 mM 0.0484 mL 0.2420 mL 0.4840 mL 1.2099 mL
80 mM 0.0363 mL 0.1815 mL 0.3630 mL 0.9075 mL
100 mM 0.0290 mL 0.1452 mL 0.2904 mL 0.7260 mL
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UNC-CA2-103 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UNC-CA2-103OthersS-phaseG2/M checkpointInhibitorinhibitorinhibit

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UNC-CA2-103
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HY-162426
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