2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Urea-15N2

Urea-15N2  (Synonyms: Carbamide-15N2; Carbonyldiamide-15N2)

Cat. No.: HY-Y0271S Purity: ≥98.0%
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Urea-15N2 is the 15N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

For research use only. We do not sell to patients.

Urea-<sup>15</sup>N<sub>2</sub> Chemical Structure

Urea-15N2 Chemical Structure

CAS No. : 2067-80-3

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Based on 1 publication(s) in Google Scholar

Other Forms of Urea-15N2:

Urea-15N2 Related Antibodies

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Description

Urea-15N2 is the 15N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Urea-15N2 Related Antibodies
Molecular Weight

62.04

Formula

CH415N2O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[15NH2]C([15NH2])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (1611.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 16.1186 mL 80.5932 mL 161.1863 mL
5 mM 3.2237 mL 16.1186 mL 32.2373 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 16.1186 mL 80.5932 mL 161.1863 mL 402.9658 mL
5 mM 3.2237 mL 16.1186 mL 32.2373 mL 80.5932 mL
10 mM 1.6119 mL 8.0593 mL 16.1186 mL 40.2966 mL
15 mM 1.0746 mL 5.3729 mL 10.7458 mL 26.8644 mL
20 mM 0.8059 mL 4.0297 mL 8.0593 mL 20.1483 mL
25 mM 0.6447 mL 3.2237 mL 6.4475 mL 16.1186 mL
30 mM 0.5373 mL 2.6864 mL 5.3729 mL 13.4322 mL
40 mM 0.4030 mL 2.0148 mL 4.0297 mL 10.0741 mL
50 mM 0.3224 mL 1.6119 mL 3.2237 mL 8.0593 mL
60 mM 0.2686 mL 1.3432 mL 2.6864 mL 6.7161 mL
80 mM 0.2015 mL 1.0074 mL 2.0148 mL 5.0371 mL
100 mM 0.1612 mL 0.8059 mL 1.6119 mL 4.0297 mL
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Urea-15N2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Urea-15N22067-80-3Carbamide-15N2Carbonyldiamide-15N2Endogenous MetaboliteInhibitorinhibitorinhibit

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