Ustusolate E

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Ustusolate E is a drimane sesquiterpene with moderate cytotoxicity against HL-60 cells with an IC₅₀ value of 9.0 μM.

For research use only. We do not sell to patients.

Ustusolate E Chemical Structure

CAS No. : 1175543-06-2

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Description

Ustusolate E is a drimane sesquiterpene with moderate cytotoxicity against HL-60 cells with an IC₅₀ value of 9.0 μM^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	> 100 μM Compound: 8, Ustusolate E	Cytotoxicity against human A549 cells after 24 hrs by SRB assay Cytotoxicity against human A549 cells after 24 hrs by SRB assay	[PMID: 19769341]
HeLa	EC₅₀	5.9 μg/mL Compound: 7	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 19778087]
HL-60	IC₅₀	9 μM Compound: 8, Ustusolate E	Cytotoxicity against human HL60 cells after 72 hrs by MTT assay Cytotoxicity against human HL60 cells after 72 hrs by MTT assay	[PMID: 19769341]
L5178Y	EC₅₀	0.6 μg/mL Compound: 7	Cytotoxicity against mouse L5178Y cells by MTT assay Cytotoxicity against mouse L5178Y cells by MTT assay	[PMID: 19778087]
PC-12	EC₅₀	7.2 μg/mL Compound: 7	Cytotoxicity against rat PC12 cells by MTT assay Cytotoxicity against rat PC12 cells by MTT assay	[PMID: 19778087]

Molecular Weight

374.43

Formula

C₂₁H₂₆O₆

CAS No.

1175543-06-2

SMILES

C[C@]([C@]12O)(CCC3)[C@@](C3(C)C)([H])[C@@H](C=C1COC2=O)OC(/C=C/C=C/C=O)=O

Structure Classification

Initial Source

Microorganisms

Aspergillus ustus

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhenyu Lu, et al. Sesquiterpenoids and benzofuranoids from the marine-derived fungus Aspergillus ustus 094102. J Nat Prod. 2009 Oct;72(10):1761-7. [Content Brief]

Ustusolate E Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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