Val-Cit-PABC-DOX

Cat. No.: HY-160774: FAQs
Data Sheet Handling Instructions

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Val-Cit-PABC-DOX (compound 10109), an epsilon-poly-L-lysine-based drug conjugate, is an agent-linker conjugate for ADC by using a DNA topoisomerase I and topoisomerase II inhibitor, Doxorubicin (HY-15142), linked via the linker, Val-Cit-PABC.

For research use only. We do not sell to patients.

Val-Cit-PABC-DOX Chemical Structure

CAS No. : 1022094-34-3

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5 mg	USD 300	Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

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Topoisomerase Topo I Topo II

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target^[1]

Traditional Cytotoxic Agents

Molecular Weight

948.97

Formula

C₄₆H₅₆N₆O₁₆

CAS No.

1022094-34-3

Appearance

Solid

Color

Orange to red

SMILES

OC1=C(C(C2=CC=CC(OC)=C2C3=O)=O)C3=C(O)C4=C1C[C@](C(CO)=O)(O)C[C@@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)NC(OCC6=CC=C(C=C6)NC([C@H](CCCNC(N)=O)NC([C@@H](N)C(C)C)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Furao Zhang, et al. Epsilon-poly-l-lysine-based drug conjugate, intermediate thereof, and application thereof. WO2023078464A1.

Val-Cit-PABC-DOX Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Val-Cit-PABC-DOX1022094-34-3Drug-Linker Conjugates for ADCTopoisomeraseepsilon-poly-L-lysinedrug conjugateDNA topoisomerase Itopoisomerase IIInhibitorinhibitorinhibit

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