2. Neuronal Signaling
  3. Beta-secretase
  4. Verubecestat tosylate

Verubecestat tosylate  (Synonyms: MK-8931 tosylate)

Cat. No.: HY-16759B
Handling Instructions

Molarity Calculator

Verubecestat tosylate is an orally active, high-affinity BACE1 and BACE2 inhibitor with Ki values of 2.2 nM and 0.38 nM. Verubecestat tosylate effectively reduces Aβ40 and has the potential for Alzheimer's Disease.

For research use only. We do not sell to patients.

Verubecestat tosylate Chemical Structure

Verubecestat tosylate Chemical Structure

CAS No. : 1875153-95-9

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of Verubecestat tosylate:

Other Forms of Verubecestat tosylate:

Verubecestat tosylate Related Antibodies

Top Publications Citing Use of Products

View All Beta-secretase Isoform Specific Products:

View All Isoforms
BACE1 BACE2

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Verubecestat tosylate is an orally active, high-affinity BACE1 and BACE2 inhibitor with Ki values of 2.2 nM and 0.38 nM. Verubecestat tosylate effectively reduces Aβ40 and has the potential for Alzheimer's Disease[1][2].

Molecular Weight

581.61

Formula

C24H25F2N5O6S2
CAS No.
SMILES

O=S(O)(C1=CC=C(C=C1)C)=O.C[C@]2(CS(=O)(N(C(N)=N2)C)=O)C3=CC(NC(C4=CC=C(C=N4)F)=O)=CC=C3F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Verubecestat tosylate Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Verubecestat1875153-95-9MK-8931MK8931MK 8931Beta-secretaseBACEβ-SecretaseorallyBACE1BACE2Aβ40Alzheimer'sDiseaseInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Verubecestat tosylate
Cat. No.:
HY-16759B
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (0 KB) Français - FR (0 KB) Deutsch - DE (0 KB) Norwegian - NO (0 KB) Español - ES (0 KB) Swedish - SV (0 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.