2. Neuronal Signaling
  3. Beta-secretase
  4. Verubecestat tosylate

Verubecestat tosylate  (Synonyms: MK-8931 tosylate)

Cat. No.: HY-16759B
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Verubecestat tosylate is an orally active, high-affinity BACE1 and BACE2 inhibitor with Ki values of 2.2 nM and 0.38 nM. Verubecestat tosylate effectively reduces Aβ40 and has the potential for Alzheimer's Disease.

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Verubecestat tosylate Chemical Structure

Verubecestat tosylate Chemical Structure

CAS No. : 1875153-95-9

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Verubecestat tosylate Related Antibodies

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Description

Verubecestat tosylate is an orally active, high-affinity BACE1 and BACE2 inhibitor with Ki values of 2.2 nM and 0.38 nM. Verubecestat tosylate effectively reduces Aβ40 and has the potential for Alzheimer's Disease[1][2].

Molecular Weight

581.61

Formula

C24H25F2N5O6S2
CAS No.
SMILES

O=S(O)(C1=CC=C(C=C1)C)=O.C[C@]2(CS(=O)(N(C(N)=N2)C)=O)C3=CC(NC(C4=CC=C(C=N4)F)=O)=CC=C3F
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Verubecestat tosylate Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Verubecestat1875153-95-9MK-8931MK8931MK 8931Beta-secretaseBACEβ-SecretaseorallyBACE1BACE2Aβ40Alzheimer'sDiseaseInhibitorinhibitorinhibit

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