1. Natural Products
  2. Disease Research Fields Plants Alkaloids
  3. Apocynaceae Cancer Indole Alkaloids
  4. Catharanthus roseus (L.) G. Don
  5. Vindolinine

Vindolinine is a natural alkaloide that can be found in Catharanthus roseus.

For research use only. We do not sell to patients.

Vindolinine Chemical Structure

Vindolinine Chemical Structure

CAS No. : 5980-02-9

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Description

Vindolinine is a natural alkaloide that can be found in Catharanthus roseus[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
26.3 μM
Compound: 7
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
[PMID: 20462230]
HL-60 IC50
6.8 μM
Compound: 7
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
[PMID: 20462230]
MCF7 IC50
21.9 μM
Compound: 7
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
[PMID: 20462230]
SMMC-7721 IC50
20.7 μM
Compound: 7
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
[PMID: 20462230]
SW480 IC50
15.2 μM
Compound: 7
Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
[PMID: 20462230]
Molecular Weight

336.43

Formula

C21H24N2O2

CAS No.
SMILES

COC([C@H]1[C@@]23[C@]4(C5=CC=CC=C5N3)[C@]6([H])[C@](C1)(C=CCN6CC4)[C@H]2C)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Molarity Calculator

  • Dilution Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Vindolinine
Cat. No.:
HY-N5122
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