2. Cell Cycle/DNA Damage
  3. Checkpoint Kinase (Chk)
  4. VRX0466617

VRX0466617, a selective Chk2 inhibitor, inhibits the phosphorylation of Chk2 Ser 19 and Ser33-35. VRX0466617 can be used in the study of cancer.

For research use only. We do not sell to patients.

VRX0466617 Chemical Structure

VRX0466617 Chemical Structure

CAS No. : 926906-64-1

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Based on 1 publication(s) in Google Scholar

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Description

VRX0466617, a selective Chk2 inhibitor, inhibits the phosphorylation of Chk2 Ser 19 and Ser33-35. VRX0466617 can be used in the study of cancer[1].

Molecular Weight

462.36

Formula

C19H20BrN5O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OCC(C)NC(C(C(NS1)=O)=C1NC2=CC=C(NC3=CC=C(Br)C=C3)C=C2)=N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
References
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VRX0466617 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VRX0466617926906-64-1VRX 0466617VRX-0466617Checkpoint Kinase (Chk)cancerChk2 Ser19Chk2 Ser33-35Inhibitorinhibitorinhibit

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