2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. Wasabi Receptor Toxin

Wasabi Receptor Toxin is a cell-penetrating scorpion toxin. Wasabi Receptor Toxin is the activator for TRPA1 ion channel with EC50 in nanomolar level, and prolongs the channel open time, but reduces Ca2+ permeability. Wasabi Receptor Toxin causes thermal hypersensitivity and mechanical allodynia in rats, without triggering neurogenic inflammation.

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Wasabi Receptor Toxin Chemical Structure

Wasabi Receptor Toxin Chemical Structure

CAS No. : 2569291-86-5

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Other Forms of Wasabi Receptor Toxin:

Wasabi Receptor Toxin Related Antibodies

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Description

Wasabi Receptor Toxin is a cell-penetrating scorpion toxin. Wasabi Receptor Toxin is the activator for TRPA1 ion channel with EC50 in nanomolar level, and prolongs the channel open time, but reduces Ca2+ permeability. Wasabi Receptor Toxin causes thermal hypersensitivity and mechanical allodynia in rats, without triggering neurogenic inflammation[1].

Molecular Weight

3855.29

Formula

C164H245N45O53S5
CAS No.
Sequence

Ala-Ser-Pro-Gln-Gln-Ala-Lys-Tyr-Cys-Tyr-Glu-Gln-Cys-Asn-Val-Asn-Lys-Val-Pro-Phe-Asp-Gln-Cys-Tyr-Gln-Met-Cys-Ser-Pro-Leu-Glu-Arg-Ser (Disulfide bridge: Cys9-Cys27; Cys13-Cys23)
Sequence Shortening

ASPQQAKYCYEQCNVNKVPFDQCYQMCSPLERS (Disulfide bridge: Cys9-Cys27; Cys13-Cys23)
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Wasabi Receptor Toxin Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Wasabi Receptor Toxin2569291-86-5WaTxTRP ChannelTransient receptor potential channelsHEK293ThyperalgesiapainSprague Dawley ratC57BL/6J mouseInhibitorinhibitorinhibit

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