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  4. Yohimbic acid hydrate

Yohimbic acid hydrate is an amphoteric demethylated derivative of Yohimbine (HY-12715). Yohimbic acid hydrate exhibits vasodilatory action. Yohimbic acid hydrate also can be used for the research of osteoarthritis (OA).

For research use only. We do not sell to patients.

Yohimbic acid hydrate Chemical Structure

Yohimbic acid hydrate Chemical Structure

CAS No. : 207801-27-2

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5 mg USD 290 In-stock
10 mg USD 460 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Yohimbic acid hydrate is an amphoteric demethylated derivative of Yohimbine (HY-12715). Yohimbic acid hydrate exhibits vasodilatory action. Yohimbic acid hydrate also can be used for the research of osteoarthritis (OA)[1][2][3].

Molecular Weight

358.43

Formula

C20H26N2O4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[H][C@]12C3=C(CCN1C[C@]4([H])CC[C@@H]([C@@H]([C@@]4([H])C2)C(O)=O)O)C(C=CC=C5)=C5N3.O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (348.74 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7899 mL 13.9497 mL 27.8995 mL
5 mM 0.5580 mL 2.7899 mL 5.5799 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7899 mL 13.9497 mL 27.8995 mL 69.7486 mL
5 mM 0.5580 mL 2.7899 mL 5.5799 mL 13.9497 mL
10 mM 0.2790 mL 1.3950 mL 2.7899 mL 6.9749 mL
15 mM 0.1860 mL 0.9300 mL 1.8600 mL 4.6499 mL
20 mM 0.1395 mL 0.6975 mL 1.3950 mL 3.4874 mL
25 mM 0.1116 mL 0.5580 mL 1.1160 mL 2.7899 mL
30 mM 0.0930 mL 0.4650 mL 0.9300 mL 2.3250 mL
40 mM 0.0697 mL 0.3487 mL 0.6975 mL 1.7437 mL
50 mM 0.0558 mL 0.2790 mL 0.5580 mL 1.3950 mL
60 mM 0.0465 mL 0.2325 mL 0.4650 mL 1.1625 mL
80 mM 0.0349 mL 0.1744 mL 0.3487 mL 0.8719 mL
100 mM 0.0279 mL 0.1395 mL 0.2790 mL 0.6975 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Yohimbic acid hydrate
Cat. No.:
HY-121936A
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