α-Glucosidase-IN-22

Cat. No.: HY-152158 Purity: 99.13%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

α-Glucosidase-IN-22 (compound 7i), a benzimidazole, is a potent α-glucosidase inhibitor with an IC₅₀ of 0.64 μM. α-Glucosidase-IN-22 is a potent anti-diabetic agent and has the potential for type 2 diabetes mellitus (T2DM) research.

For research use only. We do not sell to patients.

α-Glucosidase-IN-22 Chemical Structure

CAS No. : 2870693-28-8

Size	Price	Stock	Quantity
5 mg	USD 270	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 430	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 900	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

285.32

Formula

C₁₄H₁₁N₃O₂S

CAS No.

2870693-28-8

Appearance

Solid

Color

Light yellow to yellow

SMILES

S=C1NC2=CC=C(C=C2N1)/N=C/C3=CC=C(C=C3O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (438.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5048 mL	17.5242 mL	35.0484 mL
5 mM	0.7010 mL	3.5048 mL	7.0097 mL
10 mM	0.3505 mL	1.7524 mL	3.5048 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.13%

Select Batch:

Data Sheet (268 KB) SDS (252 KB)

COA (247 KB) HNMR (266 KB) RP-HPLC (239 KB) MS (70 KB)

Handling Instructions (2659 KB)

References

[1]. Sardar Ali, et al. Novel 5-(Arylideneamino)-1 H-Benzo[ d]imidazole-2-thiols as Potent Anti-Diabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition, and Molecular Docking Studies. ACS Omega. 2022 Nov 23;7(48):43468-43479. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.5048 mL	17.5242 mL	35.0484 mL	87.6209 mL
	5 mM	0.7010 mL	3.5048 mL	7.0097 mL	17.5242 mL
	10 mM	0.3505 mL	1.7524 mL	3.5048 mL	8.7621 mL
	15 mM	0.2337 mL	1.1683 mL	2.3366 mL	5.8414 mL
	20 mM	0.1752 mL	0.8762 mL	1.7524 mL	4.3810 mL
	25 mM	0.1402 mL	0.7010 mL	1.4019 mL	3.5048 mL
	30 mM	0.1168 mL	0.5841 mL	1.1683 mL	2.9207 mL
	40 mM	0.0876 mL	0.4381 mL	0.8762 mL	2.1905 mL
	50 mM	0.0701 mL	0.3505 mL	0.7010 mL	1.7524 mL
	60 mM	0.0584 mL	0.2921 mL	0.5841 mL	1.4603 mL
	80 mM	0.0438 mL	0.2191 mL	0.4381 mL	1.0953 mL
	100 mM	0.0350 mL	0.1752 mL	0.3505 mL	0.8762 mL