1. Metabolic Enzyme/Protease Neuronal Signaling
  2. Glucosidase Cholinesterase (ChE)
  3. α-Glucosidase-IN-68

α-Glucosidase-IN-68 (Compound 2) is an inhibitor for α-Glucosidase, AChE, and BChE, with IC50 of 0.251, 0.774 and 0.793 μM, respectively. α-Glucosidase-IN-68 exhibits antioxidant efficacy, with IC50 of 0.69 μM and 0.02 μM, in DPPH and ABTS experiments. α-Glucosidase-IN-68 exhibits antidiabetic effect in Streptozotocin (HY-13753)-induced diabetic rat models.

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α-Glucosidase-IN-68 Chemical Structure

α-Glucosidase-IN-68 Chemical Structure

CAS No. : 1624628-01-8

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Description

α-Glucosidase-IN-68 (Compound 2) is an inhibitor for α-Glucosidase, AChE, and BChE, with IC50 of 0.251, 0.774 and 0.793 μM, respectively. α-Glucosidase-IN-68 exhibits antioxidant efficacy, with IC50 of 0.69 μM and 0.02 μM, in DPPH and ABTS experiments. α-Glucosidase-IN-68 exhibits antidiabetic effect in Streptozotocin (HY-13753)-induced diabetic rat models[1].

IC50 & Target

α-Glucosidase

0.251 μM (IC50)

AChE

0.774 μM (IC50)

BChE

0.793 μM (IC50)

Molecular Weight

546.55

Formula

C32H26F4N2O2

CAS No.
SMILES

O=C(C1=C(NC2=CC=C(F)C=C2)CC(C3=CC=C(F)C=C3)N(C4=CC=C(F)C=C4)C1C5=CC=C(F)C=C5)OCC

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
α-Glucosidase-IN-68
Cat. No.:
HY-162639
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