2. PI3K/Akt/mTOR
  3. PI3K Akt
  4. α-Linolenic acid-d5

α-Linolenic acid-d5 is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

For research use only. We do not sell to patients.

α-Linolenic acid-d<sub>5</sub> Chemical Structure

α-Linolenic acid-d5 Chemical Structure

CAS No. : 145191-04-4

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Based on 1 publication(s) in Google Scholar

Other Forms of α-Linolenic acid-d5:

α-Linolenic acid-d5 Related Antibodies

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PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

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Akt Akt1 Akt2 Akt3

  • Biological Activity

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Description

α-Linolenic acid-d5 is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

α-Linolenic acid-d5 Related Antibodies
Molecular Weight

283.46

Formula

C18H25D5O2
CAS No.
Unlabeled CAS

463-40-1
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[2H]C([2H])(C([2H])(/C=C\C/C=C\C/C=C\CCCCCCCC(O)=O)[2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (352.78 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5278 mL 17.6392 mL 35.2783 mL
5 mM 0.7056 mL 3.5278 mL 7.0557 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5278 mL 17.6392 mL 35.2783 mL 88.1959 mL
5 mM 0.7056 mL 3.5278 mL 7.0557 mL 17.6392 mL
10 mM 0.3528 mL 1.7639 mL 3.5278 mL 8.8196 mL
15 mM 0.2352 mL 1.1759 mL 2.3519 mL 5.8797 mL
20 mM 0.1764 mL 0.8820 mL 1.7639 mL 4.4098 mL
25 mM 0.1411 mL 0.7056 mL 1.4111 mL 3.5278 mL
30 mM 0.1176 mL 0.5880 mL 1.1759 mL 2.9399 mL
40 mM 0.0882 mL 0.4410 mL 0.8820 mL 2.2049 mL
50 mM 0.0706 mL 0.3528 mL 0.7056 mL 1.7639 mL
60 mM 0.0588 mL 0.2940 mL 0.5880 mL 1.4699 mL
80 mM 0.0441 mL 0.2205 mL 0.4410 mL 1.1024 mL
100 mM 0.0353 mL 0.1764 mL 0.3528 mL 0.8820 mL
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α-Linolenic acid-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α-Linolenic acid-d5145191-04-4PI3KAktPhosphoinositide 3-kinasePKBProtein kinase BInhibitorinhibitorinhibit

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