β-CGRP (mouse) (Synonyms: Calcitonin gene-related peptide 2 (mouse); CGRP II (mouse))

Name: β-CGRP (mouse)
Brand: MedChemExpress
SKU: HY-P0203B
Rating: 4.5 (1 reviews)

Cat. No.: HY-P0203B Purity: 99.77%: FAQs
Data Sheet SDS COA Handling Instructions

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β-CGRP (mouse) is a calcitonin gene-related peptide that induces vasodilation. β-CGRP (mouse) can be utilized in cardiovascular, pro-inflammatory, migraine and metabolic research.

For research use only. We do not sell to patients.

β-CGRP (mouse) Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 410	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of β-CGRP (mouse):

α-CGRP (mouse, rat) Get quote
α-CGRP (mouse, rat) (TFA) Get quote

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Description

β-CGRP (mouse) is a calcitonin gene-related peptide that induces vasodilation. β-CGRP (mouse) can be utilized in cardiovascular, pro-inflammatory, migraine and metabolic research^[1].

Molecular Weight

3879.29

Formula

C₁₆₅H₂₆₅N₄₉O₅₅S₂

Appearance

Solid

Color

White to off-white

Sequence

Ser-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Asp-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Leu-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asp-Val-Gly-Ser-Glu-Ala-Phe-NH2 (Disulfide bridge:Cys2-Cys7)

Sequence Shortening

SCNTATCVTHRLADLLSRSGGVLKDNFVPTDVGSEAF-NH2 (Disulfide bridge:Cys2-Cys7)

SMILES

O=C(N[C@@H](CSSC[C@@H](C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(NCC(NCC(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](C(C)C)C(N3[C@@H](CCC3)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CC4=CC=CC=C4)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC5=O)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@H]5[C@H](O)C)=O)=O)=O)=O)[C@H](CO)N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (25.78 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.2578 mL	1.2889 mL	2.5778 mL
5 mM	0.0516 mL	0.2578 mL	0.5156 mL
10 mM	0.0258 mL	0.1289 mL	0.2578 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.77%

Select Batch:

Data Sheet (291 KB) SDS (252 KB)

COA (270 KB) LCMS (93 KB)

Handling Instructions (2659 KB)

References

[1]. Whitby K, et al. Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivo. J Virol. 2005 Jul;79(14):8698-706. [Content Brief]

[2]. Xu H, et al. Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses. Immunity. 2019 Oct 15;51(4):696-708.e9. [Content Brief]

[3]. Arulmani U, et al. Effects of the calcitonin gene-related peptide (CGRP) receptor antagonist BIBN4096BS on alpha-CGRP-induced regional haemodynamic changes in anaesthetised rats. Basic Clin Pharmacol Toxicol. 2004 Jun;94(6):291-7. [Content Brief]

[4]. Park SH, et al. Role of α-CGRP in the regulation of neurotoxic responses induced by kainic acid in mice. Peptides. 2013 Jun;44:158-62. [Content Brief]

[5]. McLatchie LM, et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature. 1998 May 28;393(6683):333-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	0.2578 mL	1.2889 mL	2.5778 mL	6.4445 mL
	5 mM	0.0516 mL	0.2578 mL	0.5156 mL	1.2889 mL
	10 mM	0.0258 mL	0.1289 mL	0.2578 mL	0.6444 mL
	15 mM	0.0172 mL	0.0859 mL	0.1719 mL	0.4296 mL
	20 mM	0.0129 mL	0.0644 mL	0.1289 mL	0.3222 mL
	25 mM	0.0103 mL	0.0516 mL	0.1031 mL	0.2578 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

β-CGRP (mouse) Related Classifications

Neurological Disease Metabolic Disease Inflammation/Immunology Cardiovascular Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-CGRP (mouse)Calcitonin gene-related peptide 2 (mouse) CGRP II (mouse)CGRP ReceptorCalcitonin gene-related peptide receptorCGRPvasodilationcardiovascularpro-inflammatorymigrainemetabolicInhibitorinhibitorinhibit

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β-CGRP (mouse) (Synonyms: Calcitonin gene-related peptide 2 (mouse); CGRP II (mouse))

Customer Review

Other Forms of β-CGRP (mouse):

β-CGRP (mouse) Related Antibodies

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

β-CGRP (mouse) Related Classifications

Keywords:

Your Recently Viewed Products:

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