1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. β-Estradiol-6-CMO-PEG3-biotin

β-Estradiol-6-CMO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

β-Estradiol-6-CMO-PEG3-biotin Chemical Structure

β-Estradiol-6-CMO-PEG3-biotin Chemical Structure

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1 mg USD 320 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

β-Estradiol-6-CMO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable Linker

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

759.95

Formula

C38H57N5O9S

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC[C@H]2O)([H])[C@@]3([H])[C@](C(C=CC(O)=C4)=C4/C(C3)=N\OCC(NCCOCCOCCOCCNC(CCCC[C@@H]5SC[C@H](N6)[C@@H]5NC6=O)=O)=O)([H])CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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  • Dilution Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
β-Estradiol-6-CMO-PEG3-biotin
Cat. No.:
HY-130929
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