1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. β-Nicotinamide mononucleotide, reduced form disodium

β-Nicotinamide mononucleotide, reduced form disodium  (Synonyms: NMNH, reduced form disodium)

Cat. No.: HY-W615108B Purity: ≥98.0%
SDS COA Handling Instructions

β-Nicotinamide mononucleotide, reduced form disodium (β-NMN) is the oxidized form of NAD+ precursor and is a NAD+ enhancer. β-Nicotinamide mononucleotide, reduced form disodium can be reduced to dihydronicotinamide mononucleotide (NMNH). NMNH inhibits glycolysis, TCA cycle, and cell growth.

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β-Nicotinamide mononucleotide, reduced form disodium Chemical Structure

β-Nicotinamide mononucleotide, reduced form disodium Chemical Structure

CAS No. : 108347-85-9

Size Price Stock Quantity
5 mg USD 110 In-stock
10 mg USD 155 In-stock
25 mg USD 260 In-stock
50 mg USD 370 In-stock
100 mg USD 520 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

β-Nicotinamide mononucleotide, reduced form disodium (β-NMN) is the oxidized form of NAD+ precursor and is a NAD+ enhancer. β-Nicotinamide mononucleotide, reduced form disodium can be reduced to dihydronicotinamide mononucleotide (NMNH). NMNH inhibits glycolysis, TCA cycle, and cell growth[1].

Molecular Weight

380.20

Formula

C11H15N2Na2O8P

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O[C@H]1[C@@H](O)[C@H](N2C=C(CC=C2)C(N)=O)O[C@@H]1COP(O[Na])(O[Na])=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (328.77 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6302 mL 13.1510 mL 26.3019 mL
5 mM 0.5260 mL 2.6302 mL 5.2604 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.6302 mL 13.1510 mL 26.3019 mL 65.7549 mL
5 mM 0.5260 mL 2.6302 mL 5.2604 mL 13.1510 mL
10 mM 0.2630 mL 1.3151 mL 2.6302 mL 6.5755 mL
15 mM 0.1753 mL 0.8767 mL 1.7535 mL 4.3837 mL
20 mM 0.1315 mL 0.6575 mL 1.3151 mL 3.2877 mL
25 mM 0.1052 mL 0.5260 mL 1.0521 mL 2.6302 mL
30 mM 0.0877 mL 0.4384 mL 0.8767 mL 2.1918 mL
40 mM 0.0658 mL 0.3288 mL 0.6575 mL 1.6439 mL
50 mM 0.0526 mL 0.2630 mL 0.5260 mL 1.3151 mL
60 mM 0.0438 mL 0.2192 mL 0.4384 mL 1.0959 mL
80 mM 0.0329 mL 0.1644 mL 0.3288 mL 0.8219 mL
100 mM 0.0263 mL 0.1315 mL 0.2630 mL 0.6575 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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β-Nicotinamide mononucleotide, reduced form disodium
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