2. GPCR/G Protein Neuronal Signaling
  3. mAChR Adrenergic Receptor
  4. β2AR/M-receptor agonist-1

β2AR/M-receptor agonist-1 (example 131) is a muscarinic antagonist and β2 adrenoceptor agonist (MABA). β2AR/M-receptor agonist-1 shows potency to β2 adrenoceptor with an EC50 value of 9.2 nM. β2AR/M-receptor agonist-1 also has potency to muscarinic receptor with a Ki value of 30.2 nM. β2AR/M-receptor agonist-1 shows MABA potency with an EC50 value of 4.0 nM.

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β2AR/M-receptor agonist-1 Chemical Structure

β2AR/M-receptor agonist-1 Chemical Structure

CAS No. : 2230520-62-2

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β2AR/M-receptor agonist-1 Related Antibodies

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Description

β2AR/M-receptor agonist-1 (example 131) is a muscarinic antagonist and β2 adrenoceptor agonist (MABA). β2AR/M-receptor agonist-1 shows potency to β2 adrenoceptor with an EC50 value of 9.2 nM. β2AR/M-receptor agonist-1 also has potency to muscarinic receptor with a Ki value of 30.2 nM. β2AR/M-receptor agonist-1 shows MABA potency with an EC50 value of 4.0 nM[1].

In Vivo

β2AR/M-receptor agonist-1 (0.01 and 0.1 mg/kg; i.v. once) decreases the heart rate of bagle dogs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

806.82

Formula

C43H56BrN3O7
CAS No.
SMILES

O[C@@H](C1=C2C(NC(C=C2)=O)=C(C=C1)O)CNCCCOC(C=C3)=CC=C3OCCC[N+]45C[C@H](C(CC5)CC4)OC[C@@](C6CCCC6)(C7=CC=CC=C7)O.[Br-]
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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β2AR/M-receptor agonist-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β2AR/M-receptor agonist-12230520-62-2mAChRAdrenergic ReceptorMuscarinic acetylcholine receptorBeta Receptorheart ratedogMABAInhibitorinhibitorinhibit

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