1-Naphthyl PP1 hydrochloride (Synonyms: 1-NA-PP 1 hydrochloride)

Cat. No.: HY-13941B Purity: 99.83%: FAQs
Data Sheet SDS COA Handling Instructions

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1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases. 1-Naphthyl PP1 hydrochloride inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC₅₀s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively.

For research use only. We do not sell to patients.

1-Naphthyl PP1 hydrochloride Chemical Structure

CAS No. : 956025-47-1

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 88	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 88	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 128	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 256	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 410	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 660	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of 1-Naphthyl PP1 hydrochloride:

1-Naphthyl PP1 In-stock

1 Publications Citing Use of MCE 1-Naphthyl PP1 hydrochloride

•Plant J. 2019 Mar;97(5):970-983. [Abstract]

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

353.85

Formula

C₁₉H₂₀ClN₅

CAS No.

956025-47-1

Appearance

Solid

Color

Light yellow to khaki

SMILES

CC(N1N=C(C2=C3C=CC=CC3=CC=C2)C4=C(N)N=CN=C41)(C)C.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (282.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8261 mL	14.1303 mL	28.2606 mL
5 mM	0.5652 mL	2.8261 mL	5.6521 mL
10 mM	0.2826 mL	1.4130 mL	2.8261 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.83%

Select Batch:

Data Sheet (280 KB) SDS (252 KB)

COA (260 KB) LCMS (90 KB)

Handling Instructions (2659 KB)

References

[1]. Tandon M, et al. New pyrazolopyrimidine inhibitors of protein kinase d as potent anticancer agents for prostate cancer cells. PLoS One. 2013 Sep 23;8(9):e75601. [Content Brief]

[2]. Bishop AC, et al. A chemical switch for inhibitor-sensitive alleles of any protein kinase. Nature. 2000 Sep 21;407(6802):395-401. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.8261 mL	14.1303 mL	28.2606 mL	70.6514 mL
	5 mM	0.5652 mL	2.8261 mL	5.6521 mL	14.1303 mL
	10 mM	0.2826 mL	1.4130 mL	2.8261 mL	7.0651 mL
	15 mM	0.1884 mL	0.9420 mL	1.8840 mL	4.7101 mL
	20 mM	0.1413 mL	0.7065 mL	1.4130 mL	3.5326 mL
	25 mM	0.1130 mL	0.5652 mL	1.1304 mL	2.8261 mL
	30 mM	0.0942 mL	0.4710 mL	0.9420 mL	2.3550 mL
	40 mM	0.0707 mL	0.3533 mL	0.7065 mL	1.7663 mL
	50 mM	0.0565 mL	0.2826 mL	0.5652 mL	1.4130 mL
	60 mM	0.0471 mL	0.2355 mL	0.4710 mL	1.1775 mL
	80 mM	0.0353 mL	0.1766 mL	0.3533 mL	0.8831 mL
	100 mM	0.0283 mL	0.1413 mL	0.2826 mL	0.7065 mL

1-Naphthyl PP1 hydrochloride Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Naphthyl PP1956025-47-11-NA-PP 1SrcInhibitorinhibitorinhibit

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1-Naphthyl PP1 hydrochloride (Synonyms: 1-NA-PP 1 hydrochloride)

Customer Review

Other Forms of 1-Naphthyl PP1 hydrochloride:

1-Naphthyl PP1 hydrochloride Related Antibodies

1 Publications Citing Use of MCE 1-Naphthyl PP1 hydrochloride

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All Src Isoform Specific Products:

Biological Activity

Purity & Documentation

References

Customer Review

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Dilution Calculator

Complete Stock Solution Preparation Table

1-Naphthyl PP1 hydrochloride Related Classifications

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