1-Octanol-d₁₇ (Synonyms: Octanol-d₁₇)

Cat. No.: HY-W032013S Purity: 99.09%: FAQs
Data Sheet SDS COA Handling Instructions

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1-Octanol-d₁₇ is the deuterium labeled 1-Octanol[1]. 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents[2]. 1-Octanol is a highly attractive biofuel with diesel-like properties[3].

For research use only. We do not sell to patients.

1-Octanol-d<sub>17</sub> Chemical Structure

1-Octanol-d₁₇ Chemical Structure

CAS No. : 153336-13-1

Size	Price	Stock	Quantity
10 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 85	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 130	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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Other Forms of 1-Octanol-d₁₇:

1-Octanol In-stock
1-Octanol-d₂-1 Get quote
1-Octanol-d₅ Get quote

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

Biological Activity
Purity & Documentation
References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

147.33

Formula

C₈HD₁₇O

CAS No.

153336-13-1

Unlabeled CAS

111-87-5

Appearance

Liquid (Density: 0.936 g/cm³)

Color

Colorless to light yellow

SMILES

[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (678.75 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.7875 mL	33.9374 mL	67.8748 mL
5 mM	1.3575 mL	6.7875 mL	13.5750 mL
10 mM	0.6787 mL	3.3937 mL	6.7875 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.09%

Select Batch:

Data Sheet (275 KB) SDS (454 KB)

COA (252 KB) HNMR (213 KB) RP-HPLC (402 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Joksovic PM, et al. Mechanisms of inhibition of T-type calcium current in the reticular thalamic neurons by 1-octanol: implication of the protein kinase C pathway. Mol Pharmacol. 2010 Jan;77(1):87-94. [Content Brief]

[3]. Akhtar MK, et al. Microbial production of 1-octanol: A naturally excreted biofuel with diesel-like properties. Metab Eng Commun. 2014 Nov 132:1-5. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.7875 mL	33.9374 mL	67.8748 mL	169.6871 mL
	5 mM	1.3575 mL	6.7875 mL	13.5750 mL	33.9374 mL
	10 mM	0.6787 mL	3.3937 mL	6.7875 mL	16.9687 mL
	15 mM	0.4525 mL	2.2625 mL	4.5250 mL	11.3125 mL
	20 mM	0.3394 mL	1.6969 mL	3.3937 mL	8.4844 mL
	25 mM	0.2715 mL	1.3575 mL	2.7150 mL	6.7875 mL
	30 mM	0.2262 mL	1.1312 mL	2.2625 mL	5.6562 mL
	40 mM	0.1697 mL	0.8484 mL	1.6969 mL	4.2422 mL
	50 mM	0.1357 mL	0.6787 mL	1.3575 mL	3.3937 mL
	60 mM	0.1131 mL	0.5656 mL	1.1312 mL	2.8281 mL
	80 mM	0.0848 mL	0.4242 mL	0.8484 mL	2.1211 mL
	100 mM	0.0679 mL	0.3394 mL	0.6787 mL	1.6969 mL

1-Octanol-d₁₇ Related Classifications

Metabolic Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Octanol-d₁₇153336-13-1Octanol-d₁₇Calcium ChannelEndogenous MetaboliteCa2+ channelsCa channelsInhibitorinhibitorinhibit

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1-Octanol-d17 (Synonyms: Octanol-d17)

Other Forms of 1-Octanol-d17:

1-Octanol-d17 Related Antibodies