1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 1-Phenylethanamine

1-Phenylethanamine  (Synonyms: DL-α-Methylbenzylamine)

Cat. No.: HY-W012848 Purity: 99.14%
SDS COA Handling Instructions Technical Support

1-Phenylethanamine is a potential central nervous system stimulant and a related compound of β-phenylethylamine. Due to the replacement of its benzene ring with an indole group, its brain glycogenolytic activity is significantly reduced. Therefore, 1-Phenylethanamine can be used to study the impact of the chemical structure of phenylethylamine derivatives on central nervous system activity. In addition, 1-Phenylethanamine can also be used to synthesize the tyrosine kinase (tyrosine kinase) inhibitor CLM3 (HY-164413).

For research use only. We do not sell to patients.

1-Phenylethanamine Chemical Structure

1-Phenylethanamine Chemical Structure

CAS No. : 618-36-0

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Description

1-Phenylethanamine is a potential central nervous system stimulant and a related compound of β-phenylethylamine. Due to the replacement of its benzene ring with an indole group, its brain glycogenolytic activity is significantly reduced. Therefore, 1-Phenylethanamine can be used to study the impact of the chemical structure of phenylethylamine derivatives on central nervous system activity. In addition, 1-Phenylethanamine can also be used to synthesize the tyrosine kinase (tyrosine kinase) inhibitor CLM3 (HY-164413)[1][2].

Molecular Weight

121.18

Formula

C8H11N

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CC(N)C1=CC=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (825.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.2522 mL 41.2609 mL 82.5219 mL
5 mM 1.6504 mL 8.2522 mL 16.5044 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.14%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 8.2522 mL 41.2609 mL 82.5219 mL 206.3047 mL
5 mM 1.6504 mL 8.2522 mL 16.5044 mL 41.2609 mL
10 mM 0.8252 mL 4.1261 mL 8.2522 mL 20.6305 mL
15 mM 0.5501 mL 2.7507 mL 5.5015 mL 13.7536 mL
20 mM 0.4126 mL 2.0630 mL 4.1261 mL 10.3152 mL
25 mM 0.3301 mL 1.6504 mL 3.3009 mL 8.2522 mL
30 mM 0.2751 mL 1.3754 mL 2.7507 mL 6.8768 mL
40 mM 0.2063 mL 1.0315 mL 2.0630 mL 5.1576 mL
50 mM 0.1650 mL 0.8252 mL 1.6504 mL 4.1261 mL
60 mM 0.1375 mL 0.6877 mL 1.3754 mL 3.4384 mL
80 mM 0.1032 mL 0.5158 mL 1.0315 mL 2.5788 mL
100 mM 0.0825 mL 0.4126 mL 0.8252 mL 2.0630 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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1-Phenylethanamine
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HY-W012848
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