11-cis-Vaccenyl acetate

Cat. No.: HY-128900 Purity: 98.9%: FAQs
Data Sheet SDS COA Handling Instructions

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11-cis-Vaccenyl acetate is male-specific lipid that mediates aggregation behavior in both male and female flies, which activates a few dozen olfactory neurons located in T1 sensilla on the antenna of both male and female flies.

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11-cis-Vaccenyl acetate Chemical Structure

CAS No. : 6186-98-7

Size	Price	Stock	Quantity
Solvent
5 mg (161.03 mM * 100 μL in Ethanol)	USD 60	In-stock	Estimated Time of Arrival: December 31
Solvent
10 mg (161.03 mM * 200 μL in Ethanol)	USD 100	In-stock	Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
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Description	11-cis-Vaccenyl acetate is male-specific lipid that mediates aggregation behavior in both male and female flies, which activates a few dozen olfactory neurons located in T1 sensilla on the antenna of both male and female flies^[1].
Molecular Weight	310.51
Formula	C₂₀H₃₈O₂
CAS No.	6186-98-7
Appearance	Liquid
Color	Colorless to light yellow
SMILES	CC(OCCCCCCCCCC/C=C\CCCCCC)=O
Structure Classification	Others
Initial Source	Endogenous metabolite
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Solution, -20°C, 2 years
Solvent & Solubility	In Vitro: DMSO : 120 mg/mL (386.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Molarity Calculator Dilution Calculator Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Mass = Concentration × Volume × Molecular Weight * Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final) This equation is commonly abbreviated as: C₁V₁ = C₂V₂ Concentration _(start) C1 × Volume _(start) V1 = Concentration _(final) C2 × Volume _(final) V2 In Vivo: Select the appropriate dissolution method based on your experimental animal and administration route. For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents: To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day. The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution. Protocol 1 Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline Solubility: ≥ 3 mg/mL (9.66 mM); Clear solution This protocol yields a clear solution of ≥ 3 mg/mL (saturation unknown). Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (30.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL. Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution. Protocol 2 Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline) Solubility: ≥ 3 mg/mL (9.66 mM); Clear solution This protocol yields a clear solution of ≥ 3 mg/mL (saturation unknown). Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (30.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear. Protocol 3 Add each solvent one by one: 10% DMSO 90% Corn Oil Solubility: ≥ 3 mg/mL (9.66 mM); Clear solution This protocol yields a clear solution of ≥ 3 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully. Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (30.0 mg/mL) to 900 μL Corn oil, and mix evenly. In Vivo Dissolution Calculator Please enter the basic information of animal experiments: Dosage mg/kg Animal weight (per animal) g Dosing volume (per animal) μL Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments. Please enter your animal formula composition: % DMSO + % + % Tween-80 + % Saline Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak. The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE). Calculation results: Working solution concentration: mg/mL Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL). The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE). Tel: 609-228-6898 E-mail: sales@medchemexpress.com Technical Support: tech@medchemexpress.com Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline. Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution If the continuous dosing period exceeds half a month, please choose this protocol carefully. Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation	Purity: 98.9% Select Batch: Data Sheet (261 KB) SDS (393 KB) COA (237 KB) Handling Instructions (2659 KB)
References	[1]. Ha TS, et al. A pheromone receptor mediates 11-cis-vaccenyl acetate-induced responses in Drosophila. J Neurosci. 2006 Aug 23;26(34):8727-33. [Content Brief]

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.2205 mL	16.1025 mL	32.2051 mL	80.5127 mL
	5 mM	0.6441 mL	3.2205 mL	6.4410 mL	16.1025 mL
	10 mM	0.3221 mL	1.6103 mL	3.2205 mL	8.0513 mL
	15 mM	0.2147 mL	1.0735 mL	2.1470 mL	5.3675 mL
	20 mM	0.1610 mL	0.8051 mL	1.6103 mL	4.0256 mL
	25 mM	0.1288 mL	0.6441 mL	1.2882 mL	3.2205 mL
	30 mM	0.1074 mL	0.5368 mL	1.0735 mL	2.6838 mL
	40 mM	0.0805 mL	0.4026 mL	0.8051 mL	2.0128 mL
	50 mM	0.0644 mL	0.3221 mL	0.6441 mL	1.6103 mL
	60 mM	0.0537 mL	0.2684 mL	0.5368 mL	1.3419 mL
	80 mM	0.0403 mL	0.2013 mL	0.4026 mL	1.0064 mL
	100 mM	0.0322 mL	0.1610 mL	0.3221 mL	0.8051 mL