2. Metabolic Enzyme/Protease
  3. 11β-HSD
  4. 11β-HSD1-IN-14

11β-HSD1-IN-14 (Compound 17) is a selective inhibitor for 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1), with IC50 of 74 nM for human HSD1, and 603 nM for HSD1 expressed HEK293 cell.

For research use only. We do not sell to patients.

11β-HSD1-IN-14 Chemical Structure

11β-HSD1-IN-14 Chemical Structure

CAS No. : 946394-50-9

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11β-HSD1-IN-14 Related Antibodies

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Description

11β-HSD1-IN-14 (Compound 17) is a selective inhibitor for 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1), with IC50 of 74 nM for human HSD1, and 603 nM for HSD1 expressed HEK293 cell[1].

IC50 & Target

IC50: 74 nM (h 11β-HSD1)
Molecular Weight

447.47

Formula

C22H20F3N3O2S
CAS No.
SMILES

O=S(C1=CC=C(C2=CC=CC=C2)C=C1)(N3CCN(CC3)C4=NC=CC=C4C(F)(F)F)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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11β-HSD1-IN-14 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

11β-HSD1-IN-14946394-50-911β-HSD11beta-HSD11β-hydroxysteroid dehydrogenases11 beta-hydroxysteroid dehydrogenaseinsulin resistancedyslipidemiatype II diabetesInhibitorinhibitorinhibit

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