2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 16α-Hydroxyestrone

16α-Hydroxyestrone  (Synonyms: 16αOHE)

Cat. No.: HY-113344 Purity: 99.06%
COA Handling Instructions

Molarity Calculator

16α-Hydroxyestrone (16αOHE) is a major Estradiol metabolite. 16α-Hydroxyestrone (16αOHE) can be used for the research of metabolic disease.

For research use only. We do not sell to patients.

16α-Hydroxyestrone Chemical Structure

16α-Hydroxyestrone Chemical Structure

CAS No. : 566-76-7

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 396 In-stock
Solution
10 mM * 1 mL in DMSO USD 396 In-stock
Solid
1 mg USD 120 In-stock
5 mg USD 360 In-stock
10 mg USD 580 In-stock
25 mg USD 1160 In-stock
50 mg USD 1850 In-stock
100 mg USD 2960 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 2 publication(s) in Google Scholar

16α-Hydroxyestrone Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

16α-Hydroxyestrone (16αOHE) is a major Estradiol metabolite. 16α-Hydroxyestrone (16αOHE) can be used for the research of metabolic disease[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Increasing levels of active estrogen metabolites, 16α-Hydroxyestrone and E3, are associated with increasing bone mineral densit[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

16α-Hydroxyestrone Related Antibodies
Molecular Weight

286.37

Formula

C18H22O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@]1([C@](C[C@H]2O)([H])[C@]3([H])CCC4=C(C=CC(O)=C4)[C@@]3([H])CC1)C2=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 250 mg/mL (873.00 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4920 mL 17.4599 mL 34.9199 mL
5 mM 0.6984 mL 3.4920 mL 6.9840 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.06%

COA (250 KB) HNMR (284 KB) LCMS (257 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4920 mL 17.4599 mL 34.9199 mL 87.2996 mL
5 mM 0.6984 mL 3.4920 mL 6.9840 mL 17.4599 mL
10 mM 0.3492 mL 1.7460 mL 3.4920 mL 8.7300 mL
15 mM 0.2328 mL 1.1640 mL 2.3280 mL 5.8200 mL
20 mM 0.1746 mL 0.8730 mL 1.7460 mL 4.3650 mL
25 mM 0.1397 mL 0.6984 mL 1.3968 mL 3.4920 mL
30 mM 0.1164 mL 0.5820 mL 1.1640 mL 2.9100 mL
40 mM 0.0873 mL 0.4365 mL 0.8730 mL 2.1825 mL
50 mM 0.0698 mL 0.3492 mL 0.6984 mL 1.7460 mL
60 mM 0.0582 mL 0.2910 mL 0.5820 mL 1.4550 mL
80 mM 0.0436 mL 0.2182 mL 0.4365 mL 1.0912 mL
100 mM 0.0349 mL 0.1746 mL 0.3492 mL 0.8730 mL
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16α-Hydroxyestrone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

16α-Hydroxyestrone566-76-716αOHEEndogenous MetaboliteInhibitorinhibitorinhibit

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