2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 2’,3’,5’-Tri-O-acetyl adenosine

2’,3’,5’-Tri-O-acetyl adenosine  (Synonyms: Adenosine, 2',3',5'-triacetate)

Cat. No.: HY-W009016 Purity: ≥97.0%
COA Handling Instructions

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2’,3’,5’-Tri-O-acetyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).

For research use only. We do not sell to patients.

2’,3’,5’-Tri-O-acetyl adenosine Chemical Structure

2’,3’,5’-Tri-O-acetyl adenosine Chemical Structure

CAS No. : 7387-57-7

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2’,3’,5’-Tri-O-acetyl adenosine Related Antibodies

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Description

2’,3’,5’-Tri-O-acetyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

Molecular Weight

393.35

Formula

C16H19N5O7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC1=NC=NC2=C1N=CN2[C@H]3[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (254.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5423 mL 12.7113 mL 25.4227 mL
5 mM 0.5085 mL 2.5423 mL 5.0845 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.55%

COA (260 KB) HNMR (123 KB) RP-HPLC (232 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5423 mL 12.7113 mL 25.4227 mL 63.5566 mL
5 mM 0.5085 mL 2.5423 mL 5.0845 mL 12.7113 mL
10 mM 0.2542 mL 1.2711 mL 2.5423 mL 6.3557 mL
15 mM 0.1695 mL 0.8474 mL 1.6948 mL 4.2371 mL
20 mM 0.1271 mL 0.6356 mL 1.2711 mL 3.1778 mL
25 mM 0.1017 mL 0.5085 mL 1.0169 mL 2.5423 mL
30 mM 0.0847 mL 0.4237 mL 0.8474 mL 2.1186 mL
40 mM 0.0636 mL 0.3178 mL 0.6356 mL 1.5889 mL
50 mM 0.0508 mL 0.2542 mL 0.5085 mL 1.2711 mL
60 mM 0.0424 mL 0.2119 mL 0.4237 mL 1.0593 mL
80 mM 0.0318 mL 0.1589 mL 0.3178 mL 0.7945 mL
100 mM 0.0254 mL 0.1271 mL 0.2542 mL 0.6356 mL
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2’,3’,5’-Tri-O-acetyl adenosine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2’,3’,5’-Tri-O-acetyl adenosine7387-57-7Adenosine, 2',3',5'-triacetateNucleoside Antimetabolite/Analogmuscle vasodilatorInhibitorinhibitorinhibit

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