2',3'-Dideoxyuridine

Cat. No.: HY-W014306: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

2',3'-Dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

2',3'-Dideoxyuridine Chemical Structure

CAS No. : 5983-09-5

Size	Price	Stock
50 mg	USD 50	Ask For Quote & Lead Time
100 mg	USD 80	Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Cellular Effect

Cell Line	Type	Value	Description	References
MT4	EC₅₀	> 100 μM Compound: ddU	Antiviral activity against HIV1 3B infected in human MT4 cells assessed as protection from virus-induced cytopathogenicity after 4 days by MTT assay Antiviral activity against HIV1 3B infected in human MT4 cells assessed as protection from virus-induced cytopathogenicity after 4 days by MTT assay	[PMID: 19282192]
MT4	CC₅₀	> 100 μM Compound: ddU	Cytotoxicity against human MT4 cells after 96 hrs by MTT assay Cytotoxicity against human MT4 cells after 96 hrs by MTT assay	[PMID: 19282192]

Molecular Weight

212.20

Formula

C₉H₁₂N₂O₄

CAS No.

5983-09-5

Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1CC[C@H](N2C(NC(C=C2)=O)=O)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (471.25 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.7125 mL	23.5627 mL	47.1254 mL
5 mM	0.9425 mL	4.7125 mL	9.4251 mL
10 mM	0.4713 mL	2.3563 mL	4.7125 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥97.0%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (250 KB) HNMR (133 KB) OR (62 KB)

Handling Instructions (2659 KB)

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.7125 mL	23.5627 mL	47.1254 mL	117.8134 mL
	5 mM	0.9425 mL	4.7125 mL	9.4251 mL	23.5627 mL
	10 mM	0.4713 mL	2.3563 mL	4.7125 mL	11.7813 mL
	15 mM	0.3142 mL	1.5708 mL	3.1417 mL	7.8542 mL
	20 mM	0.2356 mL	1.1781 mL	2.3563 mL	5.8907 mL
	25 mM	0.1885 mL	0.9425 mL	1.8850 mL	4.7125 mL
	30 mM	0.1571 mL	0.7854 mL	1.5708 mL	3.9271 mL
	40 mM	0.1178 mL	0.5891 mL	1.1781 mL	2.9453 mL
	50 mM	0.0943 mL	0.4713 mL	0.9425 mL	2.3563 mL
	60 mM	0.0785 mL	0.3927 mL	0.7854 mL	1.9636 mL
	80 mM	0.0589 mL	0.2945 mL	0.5891 mL	1.4727 mL
	100 mM	0.0471 mL	0.2356 mL	0.4713 mL	1.1781 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.