2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. 2,4-D-d5

2,4-D-d5 is the deuterium labeled 2,4-D[1]. 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[2].

For research use only. We do not sell to patients.

2,4-D-d<sub>5</sub> Chemical Structure

2,4-D-d5 Chemical Structure

CAS No. : 352438-69-8

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Based on 1 publication(s) in Google Scholar

Other Forms of 2,4-D-d5:

2,4-D-d5 Related Antibodies

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Description

2,4-D-d5 is the deuterium labeled 2,4-D[1]. 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2,4-D-d5 Related Antibodies
Molecular Weight

226.07

Formula

C8HD5Cl2O3
CAS No.
Unlabeled CAS

94-75-7
Appearance

Solid

Color

Off-white to light yellow

SMILES

OC(C([2H])([2H])OC1=C(C([2H])=C(C([2H])=C1[2H])Cl)Cl)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (442.34 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4234 mL 22.1170 mL 44.2341 mL
5 mM 0.8847 mL 4.4234 mL 8.8468 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4234 mL 22.1170 mL 44.2341 mL 110.5852 mL
5 mM 0.8847 mL 4.4234 mL 8.8468 mL 22.1170 mL
10 mM 0.4423 mL 2.2117 mL 4.4234 mL 11.0585 mL
15 mM 0.2949 mL 1.4745 mL 2.9489 mL 7.3723 mL
20 mM 0.2212 mL 1.1059 mL 2.2117 mL 5.5293 mL
25 mM 0.1769 mL 0.8847 mL 1.7694 mL 4.4234 mL
30 mM 0.1474 mL 0.7372 mL 1.4745 mL 3.6862 mL
40 mM 0.1106 mL 0.5529 mL 1.1059 mL 2.7646 mL
50 mM 0.0885 mL 0.4423 mL 0.8847 mL 2.2117 mL
60 mM 0.0737 mL 0.3686 mL 0.7372 mL 1.8431 mL
80 mM 0.0553 mL 0.2765 mL 0.5529 mL 1.3823 mL
100 mM 0.0442 mL 0.2212 mL 0.4423 mL 1.1059 mL
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2,4-D-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2,4-D-d5352438-69-8DNA/RNA SynthesisInhibitorinhibitorinhibit

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