2,4-Difluorobenzaldehyde

Cat. No.: HY-W007410 Purity: 99.51%: FAQs
Data Sheet SDS COA Handling Instructions

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2,4-Difluorobenzaldehyde is an organic chemical, that can be used in medicine, pesticide, liquid crystal materials intermediate.

For research use only. We do not sell to patients.

2,4-Difluorobenzaldehyde Chemical Structure

CAS No. : 1550-35-2

Size	Price	Stock	Quantity
5 g	USD 30	In-stock	Estimated Time of Arrival: December 31
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50 g		Get quote

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Description

2,4-Difluorobenzaldehyde is an organic chemical, that can be used in medicine, pesticide, liquid crystal materials intermediate.

Molecular Weight

142.10

Formula

C₇H₄F₂O

CAS No.

1550-35-2

Appearance

Liquid (Density: 1.299 g/cm³)

Color

Colorless to light yellow

SMILES

FC1=CC(F)=C(C=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (703.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.0373 mL	35.1865 mL	70.3730 mL
5 mM	1.4075 mL	7.0373 mL	14.0746 mL
10 mM	0.7037 mL	3.5186 mL	7.0373 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (17.59 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (17.59 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (17.59 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.88%

Select Batch:

Data Sheet (269 KB) SDS (605 KB)

COA (247 KB) RP-HPLC (204 KB)

Handling Instructions (2659 KB)

References

[1]. 2,4-Difluorobenzaldehyde is an organic chemical, that can be used in medicine, pesticide, liquid crystal materials intermediate.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	7.0373 mL	35.1865 mL	70.3730 mL	175.9324 mL
	5 mM	1.4075 mL	7.0373 mL	14.0746 mL	35.1865 mL
	10 mM	0.7037 mL	3.5186 mL	7.0373 mL	17.5932 mL
	15 mM	0.4692 mL	2.3458 mL	4.6915 mL	11.7288 mL
	20 mM	0.3519 mL	1.7593 mL	3.5186 mL	8.7966 mL
	25 mM	0.2815 mL	1.4075 mL	2.8149 mL	7.0373 mL
	30 mM	0.2346 mL	1.1729 mL	2.3458 mL	5.8644 mL
	40 mM	0.1759 mL	0.8797 mL	1.7593 mL	4.3983 mL
	50 mM	0.1407 mL	0.7037 mL	1.4075 mL	3.5186 mL
	60 mM	0.1173 mL	0.5864 mL	1.1729 mL	2.9322 mL
	80 mM	0.0880 mL	0.4398 mL	0.8797 mL	2.1992 mL
	100 mM	0.0704 mL	0.3519 mL	0.7037 mL	1.7593 mL