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  4. 2-Bromo-6-(hydroxymethyl)pyridine

2-Bromo-6-(hydroxymethyl)pyridine  (Synonyms: 6-Bromopyridine-2-methanol)

Cat. No.: HY-32836 Purity: 99.10%
SDS COA Handling Instructions

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2-Bromo-6-(hydroxymethyl)pyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

2-Bromo-6-(hydroxymethyl)pyridine Chemical Structure

2-Bromo-6-(hydroxymethyl)pyridine Chemical Structure

CAS No. : 33674-96-3

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 33 In-stock
Solution
10 mM * 1 mL in DMSO USD 33 In-stock
Solid
5 g USD 30 In-stock
10 g USD 45 In-stock
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Based on 1 publication(s) in Google Scholar

2-Bromo-6-(hydroxymethyl)pyridine Related Antibodies

Top Publications Citing Use of Products

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  • Purity & Documentation

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Description

2-Bromo-6-(hydroxymethyl)pyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

In Vitro

It is an active pharmaceutical ingredient and an pharmaceutical adjuvant.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-Bromo-6-(hydroxymethyl)pyridine Related Antibodies
Molecular Weight

188.02

Formula

C6H6BrNO
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

OCC1=NC(Br)=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (531.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.3186 mL 26.5929 mL 53.1858 mL
5 mM 1.0637 mL 5.3186 mL 10.6372 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (13.30 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (13.30 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation

Purity: 99.60%

SDS (393 KB)

COA (244 KB) HNMR (111 KB) RP-HPLC (189 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.3186 mL 26.5929 mL 53.1858 mL 132.9646 mL
5 mM 1.0637 mL 5.3186 mL 10.6372 mL 26.5929 mL
10 mM 0.5319 mL 2.6593 mL 5.3186 mL 13.2965 mL
15 mM 0.3546 mL 1.7729 mL 3.5457 mL 8.8643 mL
20 mM 0.2659 mL 1.3296 mL 2.6593 mL 6.6482 mL
25 mM 0.2127 mL 1.0637 mL 2.1274 mL 5.3186 mL
30 mM 0.1773 mL 0.8864 mL 1.7729 mL 4.4322 mL
40 mM 0.1330 mL 0.6648 mL 1.3296 mL 3.3241 mL
50 mM 0.1064 mL 0.5319 mL 1.0637 mL 2.6593 mL
60 mM 0.0886 mL 0.4432 mL 0.8864 mL 2.2161 mL
80 mM 0.0665 mL 0.3324 mL 0.6648 mL 1.6621 mL
100 mM 0.0532 mL 0.2659 mL 0.5319 mL 1.3296 mL
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2-Bromo-6-(hydroxymethyl)pyridine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Bromo-6-(hydroxymethyl)pyridine33674-96-36-Bromopyridine-2-methanolBiochemical Assay Reagentsbiochemical reagentbiological materialorganic compoundlife scienceInhibitorinhibitorinhibit

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