2-Chloro-1,4-naphthoquinone

Cat. No.: HY-115243 Purity: 97.78%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

2-Chloro-1,4-naphthoquinone is an reactive intermediate. 2-Chloro-1,4-naphthoquinone can be used for the research of various biochemical studies.

For research use only. We do not sell to patients.

2-Chloro-1,4-naphthoquinone Chemical Structure

CAS No. : 1010-60-2

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 60	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 60	In-stock	Estimated Time of Arrival: December 31
Solid
100 mg	USD 55	In-stock	Estimated Time of Arrival: December 31
500 mg	USD 130	In-stock	Estimated Time of Arrival: December 31
1 g		Get quote
5 g		Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

2-Chloro-1,4-naphthoquinone is an reactive intermediate. 2-Chloro-1,4-naphthoquinone can be used for the research of various biochemical studies^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HL-60	IC₅₀	11.48 μM Compound: 11	Cytotoxicity against human HL60 cells after 24 hrs by MTT assay Cytotoxicity against human HL60 cells after 24 hrs by MTT assay	[PMID: 30007564]
HL-60	IC₅₀	6.32 μM Compound: 11	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 30007564]
WI-38	IC₅₀	21.58 μM Compound: 11	Cytotoxicity against human WI38 cells after 48 hrs by MTT assay Cytotoxicity against human WI38 cells after 48 hrs by MTT assay	[PMID: 30007564]

Molecular Weight

192.60

Formula

C₁₀H₅ClO₂

CAS No.

1010-60-2

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C(Cl)=CC(C2=C1C=CC=C2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (519.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.1921 mL	25.9604 mL	51.9208 mL
5 mM	1.0384 mL	5.1921 mL	10.3842 mL
10 mM	0.5192 mL	2.5960 mL	5.1921 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 97.78%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (252 KB) HNMR (119 KB) RP-HPLC (225 KB)

Handling Instructions (2659 KB)

References

[1]. Dr Anton Wagner, et al. Process for the preparation of 2-chloronaphthoquinone- (1, 4). Patent. DE1182648B.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.1921 mL	25.9604 mL	51.9208 mL	129.8020 mL
	5 mM	1.0384 mL	5.1921 mL	10.3842 mL	25.9604 mL
	10 mM	0.5192 mL	2.5960 mL	5.1921 mL	12.9802 mL
	15 mM	0.3461 mL	1.7307 mL	3.4614 mL	8.6535 mL
	20 mM	0.2596 mL	1.2980 mL	2.5960 mL	6.4901 mL
	25 mM	0.2077 mL	1.0384 mL	2.0768 mL	5.1921 mL
	30 mM	0.1731 mL	0.8653 mL	1.7307 mL	4.3267 mL
	40 mM	0.1298 mL	0.6490 mL	1.2980 mL	3.2451 mL
	50 mM	0.1038 mL	0.5192 mL	1.0384 mL	2.5960 mL
	60 mM	0.0865 mL	0.4327 mL	0.8653 mL	2.1634 mL
	80 mM	0.0649 mL	0.3245 mL	0.6490 mL	1.6225 mL
	100 mM	0.0519 mL	0.2596 mL	0.5192 mL	1.2980 mL