2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine

Cat. No.: HY-152378 Purity: 96.87%: FAQs
Data Sheet SDS COA Handling Instructions

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2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine Chemical Structure

CAS No. : 908129-24-8

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

247.18

Formula

C₈H₁₀FN₃O₅

CAS No.

908129-24-8

Appearance

Solid

Color

Off-white to light yellow

SMILES

O[C@H]1[C@H](F)[C@H](N2C(NC(C=N2)=O)=O)O[C@@H]1CO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (505.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.0456 mL	20.2282 mL	40.4563 mL
5 mM	0.8091 mL	4.0456 mL	8.0913 mL
10 mM	0.4046 mL	2.0228 mL	4.0456 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 96.87%

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Data Sheet (271 KB) SDS (252 KB)

COA (252 KB) HNMR (269 KB) RP-HPLC (259 KB) MS (69 KB)

Handling Instructions (2659 KB)

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.0456 mL	20.2282 mL	40.4563 mL	101.1409 mL
	5 mM	0.8091 mL	4.0456 mL	8.0913 mL	20.2282 mL
	10 mM	0.4046 mL	2.0228 mL	4.0456 mL	10.1141 mL
	15 mM	0.2697 mL	1.3485 mL	2.6971 mL	6.7427 mL
	20 mM	0.2023 mL	1.0114 mL	2.0228 mL	5.0570 mL
	25 mM	0.1618 mL	0.8091 mL	1.6183 mL	4.0456 mL
	30 mM	0.1349 mL	0.6743 mL	1.3485 mL	3.3714 mL
	40 mM	0.1011 mL	0.5057 mL	1.0114 mL	2.5285 mL
	50 mM	0.0809 mL	0.4046 mL	0.8091 mL	2.0228 mL
	60 mM	0.0674 mL	0.3371 mL	0.6743 mL	1.6857 mL
	80 mM	0.0506 mL	0.2529 mL	0.5057 mL	1.2643 mL
	100 mM	0.0405 mL	0.2023 mL	0.4046 mL	1.0114 mL