2. PROTAC
  3. Ligands for E3 Ligase
  4. 2-Methoxyphenyl dihydrouracil

2-Methoxyphenyl dihydrouracil (Compound 13) is a CRBN ligand, and can be used for synthesis of PROTACs.

For research use only. We do not sell to patients.

2-Methoxyphenyl dihydrouracil Chemical Structure

2-Methoxyphenyl dihydrouracil Chemical Structure

CAS No. : 2377643-33-7

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2-Methoxyphenyl dihydrouracil Related Antibodies

Top Publications Citing Use of Products

View All Ligands for E3 Ligase Isoform Specific Products:

View All Isoforms
von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1

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Description

2-Methoxyphenyl dihydrouracil (Compound 13) is a CRBN ligand, and can be used for synthesis of PROTACs[1].

IC50 & Target[1]

Cereblon

 

Molecular Weight

264.23

Formula

C12H12N2O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=CC=C(OC)C(N(C(N2)=O)CCC2=O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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2-Methoxyphenyl dihydrouracil Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Methoxyphenyl dihydrouracil2377643-33-7Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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