3-Hydroxycapric acid

Name: 3-Hydroxycapric acid
Brand: MedChemExpress
SKU: HY-113057
Rating: 4.5 (1 reviews)

Cat. No.: HY-113057 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

3-Hydroxycapric acid is an inhibitor for mitotic progression.

For research use only. We do not sell to patients.

3-Hydroxycapric acid Chemical Structure

CAS No. : 14292-26-3

Size	Price	Stock	Quantity
5 mg	USD 30	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

3-Hydroxycapric acid is an inhibitor for mitotic progression.

IC₅₀ & Target

Human Endogenous Metabolite

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	31.8 μM Compound: 23	Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulated [3H]cAMP accumulation preincubated for 5 mins followed by forskolin stimulation and measured after 15 m Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulated [3H]cAMP accumulation preincubated for 5 mins followed by forskolin stimulation and measured after 15 m	[PMID: 31721581]
CHO	EC₅₀	4.05 μM Compound: 23	Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment measured after 90 mins by beta-galactosidase based PathHunter assay Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment measured after 90 mins by beta-galactosidase based PathHunter assay	[PMID: 31721581]

In Vitro

3-Hydroxycapric acid (Myrmicacin) inhibits mitotic progression at any stage even after metaphase^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

188.26

Formula

C₁₀H₂₀O₃

CAS No.

14292-26-3

Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCC(O)CC(O)=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (531.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.3118 mL	26.5590 mL	53.1180 mL
5 mM	1.0624 mL	5.3118 mL	10.6236 mL
10 mM	0.5312 mL	2.6559 mL	5.3118 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Volume _(start)

Concentration _(final)

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (265 KB) SDS (393 KB)

COA (241 KB) HNMR (244 KB) MS (173 KB)

Handling Instructions (2659 KB)

References

[1]. Iwanami Y. et al. Myrmicacin, a new inhibitor for mitotic progression after metaphase. Protoplasma. 1978;95(3):267-71. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.3118 mL	26.5590 mL	53.1180 mL	132.7951 mL
	5 mM	1.0624 mL	5.3118 mL	10.6236 mL	26.5590 mL
	10 mM	0.5312 mL	2.6559 mL	5.3118 mL	13.2795 mL
	15 mM	0.3541 mL	1.7706 mL	3.5412 mL	8.8530 mL
	20 mM	0.2656 mL	1.3280 mL	2.6559 mL	6.6398 mL
	25 mM	0.2125 mL	1.0624 mL	2.1247 mL	5.3118 mL
	30 mM	0.1771 mL	0.8853 mL	1.7706 mL	4.4265 mL
	40 mM	0.1328 mL	0.6640 mL	1.3280 mL	3.3199 mL
	50 mM	0.1062 mL	0.5312 mL	1.0624 mL	2.6559 mL
	60 mM	0.0885 mL	0.4427 mL	0.8853 mL	2.2133 mL
	80 mM	0.0664 mL	0.3320 mL	0.6640 mL	1.6599 mL
	100 mM	0.0531 mL	0.2656 mL	0.5312 mL	1.3280 mL