4-Morpholinoaniline

Cat. No.: HY-75777 Purity: 95.00%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

4-Morpholinoaniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

4-Morpholinoaniline Chemical Structure

CAS No. : 2524-67-6

Size	Price	Stock
25 g	USD 30	Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

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Description

4-Morpholinoaniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Molecular Weight

178.23

Formula

C₁₀H₁₄N₂O

CAS No.

2524-67-6

Appearance

Solid

Color

Brown to black

SMILES

NC1=CC=C(N2CCOCC2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (561.07 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.6107 mL	28.0536 mL	56.1073 mL
5 mM	1.1221 mL	5.6107 mL	11.2215 mL
10 mM	0.5611 mL	2.8054 mL	5.6107 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (14.03 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (14.03 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.32%

Select Batch:

Data Sheet (242 KB) SDS (393 KB)

COA (245 KB) HNMR (129 KB) RP-HPLC (241 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.6107 mL	28.0536 mL	56.1073 mL	140.2682 mL
	5 mM	1.1221 mL	5.6107 mL	11.2215 mL	28.0536 mL
	10 mM	0.5611 mL	2.8054 mL	5.6107 mL	14.0268 mL
	15 mM	0.3740 mL	1.8702 mL	3.7405 mL	9.3512 mL
	20 mM	0.2805 mL	1.4027 mL	2.8054 mL	7.0134 mL
	25 mM	0.2244 mL	1.1221 mL	2.2443 mL	5.6107 mL
	30 mM	0.1870 mL	0.9351 mL	1.8702 mL	4.6756 mL
	40 mM	0.1403 mL	0.7013 mL	1.4027 mL	3.5067 mL
	50 mM	0.1122 mL	0.5611 mL	1.1221 mL	2.8054 mL
	60 mM	0.0935 mL	0.4676 mL	0.9351 mL	2.3378 mL
	80 mM	0.0701 mL	0.3507 mL	0.7013 mL	1.7534 mL
	100 mM	0.0561 mL	0.2805 mL	0.5611 mL	1.4027 mL