4-Thiothymidine

Cat. No.: HY-W587829 Purity: 99.67%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

4-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

4-Thiothymidine Chemical Structure

CAS No. : 7236-57-9

Size	Price	Stock	Quantity
Free Sample (0.1 - 0.5 mg)		Apply Now
25 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 75	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Purity & Documentation
References
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Description

Molecular Weight

258.29

Formula

C₁₀H₁₄N₂O₄S

CAS No.

7236-57-9

Appearance

Solid

Color

Light yellow to light brown

SMILES

OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(C)=C2)=S)=O)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (483.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.8716 mL	19.3581 mL	38.7162 mL
5 mM	0.7743 mL	3.8716 mL	7.7432 mL
10 mM	0.3872 mL	1.9358 mL	3.8716 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.67%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (251 KB) HNMR (261 KB) LCMS (94 KB)

Handling Instructions (2659 KB)

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.8716 mL	19.3581 mL	38.7162 mL	96.7904 mL
	5 mM	0.7743 mL	3.8716 mL	7.7432 mL	19.3581 mL
	10 mM	0.3872 mL	1.9358 mL	3.8716 mL	9.6790 mL
	15 mM	0.2581 mL	1.2905 mL	2.5811 mL	6.4527 mL
	20 mM	0.1936 mL	0.9679 mL	1.9358 mL	4.8395 mL
	25 mM	0.1549 mL	0.7743 mL	1.5486 mL	3.8716 mL
	30 mM	0.1291 mL	0.6453 mL	1.2905 mL	3.2263 mL
	40 mM	0.0968 mL	0.4840 mL	0.9679 mL	2.4198 mL
	50 mM	0.0774 mL	0.3872 mL	0.7743 mL	1.9358 mL
	60 mM	0.0645 mL	0.3226 mL	0.6453 mL	1.6132 mL
	80 mM	0.0484 mL	0.2420 mL	0.4840 mL	1.2099 mL
	100 mM	0.0387 mL	0.1936 mL	0.3872 mL	0.9679 mL

4-Thiothymidine Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Thiothymidine7236-57-9Nucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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