2. Anti-infection
  3. Fungal Influenza Virus
  4. 5-Aminouridine

5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. 5-Aminouridine exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses.

For research use only. We do not sell to patients.

5-Aminouridine Chemical Structure

5-Aminouridine Chemical Structure

CAS No. : 2149-76-0

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1 mg USD 34 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

5-Aminouridine Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. 5-Aminouridine exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses[1][2][3].

In Vitro

This modified nucleobase, 5-Aminouridine, must exhibit a low enough potential to be oxidized by Os(bpy)33+. These modified nucleobases can be inserted into the target DNA by direct synthesis using modified phosphoramidites[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

5-Aminouridine Related Antibodies
In Vivo

5-Aminouridine inhibits incorporation of carbamylaspartate into pyrimidines of both RNA and DNA in rat lived and [32P]phosphate into phospholipids and RNA nucleotides of rat liver slices and hepatoma[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

259.22

Formula

C9H13N3O6
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N(C(N2)=O)C=C(N)C2=O)O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 25 mg/mL (96.44 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8577 mL 19.2886 mL 38.5773 mL
5 mM 0.7715 mL 3.8577 mL 7.7155 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.8577 mL 19.2886 mL 38.5773 mL 96.4432 mL
5 mM 0.7715 mL 3.8577 mL 7.7155 mL 19.2886 mL
10 mM 0.3858 mL 1.9289 mL 3.8577 mL 9.6443 mL
15 mM 0.2572 mL 1.2859 mL 2.5718 mL 6.4295 mL
20 mM 0.1929 mL 0.9644 mL 1.9289 mL 4.8222 mL
25 mM 0.1543 mL 0.7715 mL 1.5431 mL 3.8577 mL
30 mM 0.1286 mL 0.6430 mL 1.2859 mL 3.2148 mL
40 mM 0.0964 mL 0.4822 mL 0.9644 mL 2.4111 mL
50 mM 0.0772 mL 0.3858 mL 0.7715 mL 1.9289 mL
60 mM 0.0643 mL 0.3215 mL 0.6430 mL 1.6074 mL
80 mM 0.0482 mL 0.2411 mL 0.4822 mL 1.2055 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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5-Aminouridine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Aminouridine2149-76-0FungalInfluenza VirusDNAtargetnucleobasespyrimidinesanti-tumorfungivirusesInhibitorinhibitorinhibit

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