1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) 

Cat. No.: HY-148503 Purity: 98.55%
COA Handling Instructions

5'-ODMT cEt N-Bz A Phosphoramidite Amidite is a locked nucleic acid (LNA) analogue. 5'-ODMT cEt N-Bz A Phosphoramidite Amidite possesses hybridization and mismatch discrimination attributes similar to those of LNA and shows resistance to exonuclease digestion.

For research use only. We do not sell to patients.

5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) Chemical Structure

5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) Chemical Structure

CAS No. : 1197033-19-4

Size Price Stock Quantity
10 mg USD 50 In-stock
25 mg USD 90 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

5'-ODMT cEt N-Bz A Phosphoramidite Amidite is a locked nucleic acid (LNA) analogue. 5'-ODMT cEt N-Bz A Phosphoramidite Amidite possesses hybridization and mismatch discrimination attributes similar to those of LNA and shows resistance to exonuclease digestion[1].

Molecular Weight

899.97

Formula

C49H54N7O8P

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC(C=C1)=CC=C1C(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)OC[C@]45[C@H]([C@](O[C@H]5C)([H])[C@H](N6C7=NC=NC(NC(C8=CC=CC=C8)=O)=C7N=C6)O4)OP(OCCC#N)N(C(C)C)C(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (111.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1111 mL 5.5557 mL 11.1115 mL
5 mM 0.2222 mL 1.1111 mL 2.2223 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1111 mL 5.5557 mL 11.1115 mL 27.7787 mL
5 mM 0.2222 mL 1.1111 mL 2.2223 mL 5.5557 mL
10 mM 0.1111 mL 0.5556 mL 1.1111 mL 2.7779 mL
15 mM 0.0741 mL 0.3704 mL 0.7408 mL 1.8519 mL
20 mM 0.0556 mL 0.2778 mL 0.5556 mL 1.3889 mL
25 mM 0.0444 mL 0.2222 mL 0.4445 mL 1.1111 mL
30 mM 0.0370 mL 0.1852 mL 0.3704 mL 0.9260 mL
40 mM 0.0278 mL 0.1389 mL 0.2778 mL 0.6945 mL
50 mM 0.0222 mL 0.1111 mL 0.2222 mL 0.5556 mL
60 mM 0.0185 mL 0.0926 mL 0.1852 mL 0.4630 mL
80 mM 0.0139 mL 0.0694 mL 0.1389 mL 0.3472 mL
100 mM 0.0111 mL 0.0556 mL 0.1111 mL 0.2778 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)
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HY-148503
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