5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

Cat. No.: HY-148503 Purity: 98.55%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

5'-ODMT cEt N-Bz A Phosphoramidite Amidite is a locked nucleic acid (LNA) analogue. 5'-ODMT cEt N-Bz A Phosphoramidite Amidite possesses hybridization and mismatch discrimination attributes similar to those of LNA and shows resistance to exonuclease digestion.

For research use only. We do not sell to patients.

5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) Chemical Structure

CAS No. : 1197033-19-4

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 55	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 55	In-stock	Estimated Time of Arrival: December 31
Solid
10 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 90	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

899.97

Formula

C₄₉H₅₄N₇O₈P

CAS No.

1197033-19-4

Appearance

Solid

Color

White to off-white

SMILES

COC(C=C1)=CC=C1C(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)OC[C@]45[C@H]([C@](O[C@H]5C)([H])[C@H](N6C7=NC=NC(NC(C8=CC=CC=C8)=O)=C7N=C6)O4)OP(OCCC#N)N(C(C)C)C(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (111.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1111 mL	5.5557 mL	11.1115 mL
5 mM	0.2222 mL	1.1111 mL	2.2223 mL
10 mM	0.1111 mL	0.5556 mL	1.1111 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.55%

Select Batch:

Data Sheet (277 KB) SDS (252 KB)

COA (263 KB) HNMR (335 KB) RP-HPLC (244 KB)

Handling Instructions (2659 KB)

References

[1]. Seth PP, et al. Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analogues. J Org Chem. 2010 Mar 5;75(5):1569-81. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.1111 mL	5.5557 mL	11.1115 mL	27.7787 mL
	5 mM	0.2222 mL	1.1111 mL	2.2223 mL	5.5557 mL
	10 mM	0.1111 mL	0.5556 mL	1.1111 mL	2.7779 mL
	15 mM	0.0741 mL	0.3704 mL	0.7408 mL	1.8519 mL
	20 mM	0.0556 mL	0.2778 mL	0.5556 mL	1.3889 mL
	25 mM	0.0444 mL	0.2222 mL	0.4445 mL	1.1111 mL
	30 mM	0.0370 mL	0.1852 mL	0.3704 mL	0.9260 mL
	40 mM	0.0278 mL	0.1389 mL	0.2778 mL	0.6945 mL
	50 mM	0.0222 mL	0.1111 mL	0.2222 mL	0.5556 mL
	60 mM	0.0185 mL	0.0926 mL	0.1852 mL	0.4630 mL
	80 mM	0.0139 mL	0.0694 mL	0.1389 mL	0.3472 mL
	100 mM	0.0111 mL	0.0556 mL	0.1111 mL	0.2778 mL