2. Metabolic Enzyme/Protease Cell Cycle/DNA Damage
  3. Endogenous Metabolite DNA/RNA Synthesis
  4. Guanosine 5'-triphosphate trisodium salt hydrate

Guanosine 5'-triphosphate trisodium salt hydrate  (Synonyms: 5'-GTP trisodium salt hydrate)

Cat. No.: HY-12695B Purity: ≥95.0%
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5'-GTP trisodium salt hydrate is an activator of the signal transducing G proteins and also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

For research use only. We do not sell to patients.

Guanosine 5'-triphosphate trisodium salt hydrate Chemical Structure

Guanosine 5'-triphosphate trisodium salt hydrate Chemical Structure

CAS No. : 207300-85-4

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Based on 6 publication(s) in Google Scholar

Other Forms of Guanosine 5'-triphosphate trisodium salt hydrate:

Guanosine 5'-triphosphate trisodium salt hydrate Related Antibodies

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Description

5'-GTP trisodium salt hydrate is an activator of the signal transducing G proteins and also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

589.13

Formula

C10H13N5Na3O14P3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(OP(OP(O)(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2NC(N)=NC3=O)O1)=O)(O[Na])=O)(O[Na])O[Na].[xH2O]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 150 mg/mL (254.61 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6974 mL 8.4871 mL 16.9742 mL
5 mM 0.3395 mL 1.6974 mL 3.3948 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥95.0%

COA (253 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.6974 mL 8.4871 mL 16.9742 mL 42.4355 mL
5 mM 0.3395 mL 1.6974 mL 3.3948 mL 8.4871 mL
10 mM 0.1697 mL 0.8487 mL 1.6974 mL 4.2435 mL
15 mM 0.1132 mL 0.5658 mL 1.1316 mL 2.8290 mL
20 mM 0.0849 mL 0.4244 mL 0.8487 mL 2.1218 mL
25 mM 0.0679 mL 0.3395 mL 0.6790 mL 1.6974 mL
30 mM 0.0566 mL 0.2829 mL 0.5658 mL 1.4145 mL
40 mM 0.0424 mL 0.2122 mL 0.4244 mL 1.0609 mL
50 mM 0.0339 mL 0.1697 mL 0.3395 mL 0.8487 mL
60 mM 0.0283 mL 0.1415 mL 0.2829 mL 0.7073 mL
80 mM 0.0212 mL 0.1061 mL 0.2122 mL 0.5304 mL
100 mM 0.0170 mL 0.0849 mL 0.1697 mL 0.4244 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Guanosine 5'-triphosphate trisodium salt hydrate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Guanosine 5'-triphosphate trisodium salt207300-85-45'-GTP trisodium saltEndogenous MetaboliteDNA/RNA SynthesisInhibitorinhibitorinhibit

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