2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. 6-Aminonicotinic acid

6-Aminonicotinic acid is a GABAA receptor agonist with Ki value of 4.4 nM.

For research use only. We do not sell to patients.

6-Aminonicotinic acid Chemical Structure

6-Aminonicotinic acid Chemical Structure

CAS No. : 3167-49-5

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6-Aminonicotinic acid Related Antibodies

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Description

6-Aminonicotinic acid is a GABAA receptor agonist with Ki value of 4.4 nM[1].

Molecular Weight

138.12

Formula

C6H6N2O2
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C(O)C1=CN=C(N)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 2.5 mg/mL (18.10 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.2401 mL 36.2004 mL 72.4008 mL
5 mM 1.4480 mL 7.2401 mL 14.4802 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.86%

SDS (393 KB)

COA (245 KB) HNMR (128 KB) RP-HPLC (244 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.2401 mL 36.2004 mL 72.4008 mL 181.0020 mL
5 mM 1.4480 mL 7.2401 mL 14.4802 mL 36.2004 mL
10 mM 0.7240 mL 3.6200 mL 7.2401 mL 18.1002 mL
15 mM 0.4827 mL 2.4134 mL 4.8267 mL 12.0668 mL
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6-Aminonicotinic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Aminonicotinic acid3167-49-5GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorInhibitorinhibitorinhibit

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