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  3. 7-Amino-3-chloro cephalosporanic acid

7-Amino-3-chloro cephalosporanic acid  (Synonyms: 7-ACCA)

Cat. No.: HY-131124 Purity: 99.29%
SDS COA Handling Instructions

7-Amino-3-chloro cephalosporanic acid (7-ACCA) is an important intermediate for the synthesis of the second generation cephalosporins Cefaclor (HY-B0198).

For research use only. We do not sell to patients.

7-Amino-3-chloro cephalosporanic acid Chemical Structure

7-Amino-3-chloro cephalosporanic acid Chemical Structure

CAS No. : 53994-69-7

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Based on 1 publication(s) in Google Scholar

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Description

7-Amino-3-chloro cephalosporanic acid (7-ACCA) is an important intermediate for the synthesis of the second generation cephalosporins Cefaclor (HY-B0198)[1].

Molecular Weight

234.66

Formula

C7H7ClN2O3S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C(N12)=C(Cl)CS[C@]2([H])[C@H](N)C1=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

0.1 M Sodium carbonate : 40 mg/mL (170.46 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2615 mL 21.3074 mL 42.6148 mL
5 mM 0.8523 mL 4.2615 mL 8.5230 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
0.1 M Sodium carbonate 1 mM 4.2615 mL 21.3074 mL 42.6148 mL 106.5371 mL
5 mM 0.8523 mL 4.2615 mL 8.5230 mL 21.3074 mL
10 mM 0.4261 mL 2.1307 mL 4.2615 mL 10.6537 mL
15 mM 0.2841 mL 1.4205 mL 2.8410 mL 7.1025 mL
20 mM 0.2131 mL 1.0654 mL 2.1307 mL 5.3269 mL
25 mM 0.1705 mL 0.8523 mL 1.7046 mL 4.2615 mL
30 mM 0.1420 mL 0.7102 mL 1.4205 mL 3.5512 mL
40 mM 0.1065 mL 0.5327 mL 1.0654 mL 2.6634 mL
50 mM 0.0852 mL 0.4261 mL 0.8523 mL 2.1307 mL
60 mM 0.0710 mL 0.3551 mL 0.7102 mL 1.7756 mL
80 mM 0.0533 mL 0.2663 mL 0.5327 mL 1.3317 mL
100 mM 0.0426 mL 0.2131 mL 0.4261 mL 1.0654 mL
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7-Amino-3-chloro cephalosporanic acid Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
7-Amino-3-chloro cephalosporanic acid
Cat. No.:
HY-131124
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