2. Metabolic Enzyme/Protease Others
  3. Cytochrome P450 Fluorescent Dye
  4. 7-Methoxy-4-(trifluoromethyl)coumarin

7-Methoxy-4-(trifluoromethyl)coumarin  (Synonyms: MFC)

Cat. No.: HY-W027773 Purity: ≥98.0%
SDS
COA
Handling Instructions Technical Support

7-Methoxy-4-(trifluoromethyl)coumarin (MFC) is a fluorescent substrate for cytochrome P450 and can quantify CYP activity.

For research use only. We do not sell to patients.

7-Methoxy-4-(trifluoromethyl)coumarin Chemical Structure

7-Methoxy-4-(trifluoromethyl)coumarin Chemical Structure

CAS No. : 575-04-2

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7-Methoxy-4-(trifluoromethyl)coumarin Related Antibodies

Top Publications Citing Use of Products

View All Cytochrome P450 Isoform Specific Products:

View All Isoforms
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

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Description

7-Methoxy-4-(trifluoromethyl)coumarin (MFC) is a fluorescent substrate for cytochrome P450 and can quantify CYP activity[1].

Molecular Weight

244.17

Formula

C11H7F3O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1OC2=CC(OC)=CC=C2C(C(F)(F)F)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 4 mg/mL (16.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0955 mL 20.4775 mL 40.9551 mL
5 mM 0.8191 mL 4.0955 mL 8.1910 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

SDS (393 KB)

COA (249 KB) HNMR (129 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.0955 mL 20.4775 mL 40.9551 mL 102.3877 mL
5 mM 0.8191 mL 4.0955 mL 8.1910 mL 20.4775 mL
10 mM 0.4096 mL 2.0478 mL 4.0955 mL 10.2388 mL
15 mM 0.2730 mL 1.3652 mL 2.7303 mL 6.8258 mL
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7-Methoxy-4-(trifluoromethyl)coumarin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7-Methoxy-4-(trifluoromethyl)coumarin575-04-2MFCCytochrome P450Fluorescent DyeCYPscytochrome P450Inhibitorinhibitorinhibit

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