2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 8-Bromo-2'-deoxyadenosine

8-Bromo-2'-deoxyadenosine  (Synonyms: 8-Bromo-9-(2-deoxypentofuranosyl)-9H-purin-6-amine)

Cat. No.: HY-W013052
Handling Instructions Technical Support

8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

8-Bromo-2'-deoxyadenosine Chemical Structure

8-Bromo-2'-deoxyadenosine Chemical Structure

CAS No. : 14985-44-5

Size Price Stock
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO Ask For Quote & Lead Time
Solid
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100 mg Ask For Quote & Lead Time

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8-Bromo-2'-deoxyadenosine Related Antibodies

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Description

8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Molecular Weight

330.14

Formula

C10H12BrN5O3
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

OC[C@@H]1[C@@H](O)C[C@H](N2C(Br)=NC3=C2N=CN=C3N)O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (302.90 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0290 mL 15.1451 mL 30.2902 mL
5 mM 0.6058 mL 3.0290 mL 6.0580 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0290 mL 15.1451 mL 30.2902 mL 75.7254 mL
5 mM 0.6058 mL 3.0290 mL 6.0580 mL 15.1451 mL
10 mM 0.3029 mL 1.5145 mL 3.0290 mL 7.5725 mL
15 mM 0.2019 mL 1.0097 mL 2.0193 mL 5.0484 mL
20 mM 0.1515 mL 0.7573 mL 1.5145 mL 3.7863 mL
25 mM 0.1212 mL 0.6058 mL 1.2116 mL 3.0290 mL
30 mM 0.1010 mL 0.5048 mL 1.0097 mL 2.5242 mL
40 mM 0.0757 mL 0.3786 mL 0.7573 mL 1.8931 mL
50 mM 0.0606 mL 0.3029 mL 0.6058 mL 1.5145 mL
60 mM 0.0505 mL 0.2524 mL 0.5048 mL 1.2621 mL
80 mM 0.0379 mL 0.1893 mL 0.3786 mL 0.9466 mL
100 mM 0.0303 mL 0.1515 mL 0.3029 mL 0.7573 mL
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8-Bromo-2'-deoxyadenosine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

8-Bromo-2'-deoxyadenosine14985-44-58-Bromo-9-(2-deoxypentofuranosyl)-9H-purin-6-amineNucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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